The molecular analysis of synonymy among medically important yeasts within the genus Candida

B. L. Wickes, J. B. Hicks, W. G. Merz, K. J. Kwon-Chung

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22 Scopus citations


Three sets of medically important yeasts, Candida albicans, C. tropicalis, and C. krusei, were compared with their putative synonyms (C. langeronii and C. claussenii, C. paratropicalis, and Itssatchenkia orientalis, respectively) to determine if these synonyms are genetically distinguishable from each other. Pulsed-field electrophoresis and hybridization to species-specific probes were used to accomplish this goal. The species-specific probes for C. albicans and C. tropicalis have been previously described (27A and CT13.8, respectively) whereas the probe for C krusei (CK3) was cloned in this study. No distinguishing characteristics between synonyms were identified, thus supporting the current taxonomic treatment of these organisms.

Original languageEnglish (US)
Pages (from-to)901-907
Number of pages7
JournalJournal of General Microbiology
Issue number5
Publication statusPublished - Jan 1 1992


ASJC Scopus subject areas

  • Microbiology

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