DER INTRAHEPATISCHE PORTOSYSTEMISCHE SHUNT. ERSTE KLINISCHE ERFAHRUNGEN BEI PATIENTEN MIT LEBERZIRRHOSE

Translated title of the contribution: The intrahepatic portosystemic shunt: Early clinical experience in liver cirrhosis patients

M. Rossle, G. M. Richter, G. Noeldge, V. Siegerstetter, J. C. Palmaz, W. Wenz, W. Gerok

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

A new non-operative catheter technique to perform an intrahepatic portosystemic shunt by transjugular approach was applied to ten patients with recurrent bleeding from oesophageal and fundal varices. Therefore a balloon-expandable stent was placed between a portal vein and a hepatic vein. Implantation of the stent was successful in seven of the ten patients. Two of these seven patients died 10 and 11 days, respectively, after the procedure, one of them in consequence of respiratory failure, the other due to an uncontrollable bleeding from the site of the percutaneous transhepatic puncture because of a marked clotting disorder. The intrahepatic shunt construction led to a mean reduction of the pressure gradient between portal and hepatic vein of 40%. No recurrence of variceal haemorrhage occurred during the average follow-up time of 5.6 months (3-9 months). One patient developed several episodes of portosystemic encephalopathy. The transjugular intrahepatic portosystemic shunt is effective in the treatment of portal hypertension and might become an alternative to shunt surgery.

Translated title of the contributionThe intrahepatic portosystemic shunt: Early clinical experience in liver cirrhosis patients
Original languageGerman
Pages (from-to)1511-1516
Number of pages6
JournalDeutsche Medizinische Wochenschrift
Volume114
Issue number40
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Medicine(all)

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