Abstract
Endopeptidase 24.15 (EC 3.4.24.15; EP24.15) and endopeptidase 24.16 (EC 3.4.24.16; EP24.16) are enzymes involved in general peptide metabolism in mammalian cells and tissues. This review will focus on morphological and biochemical aspects related to the subcellular distribution and secretion of these homologous enzymes in the central nervous system. These are important issues for a better understanding of the functions of EP24.15 and EP24.16 within neuroendocrine systems.
Original language | English (US) |
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Pages (from-to) | 415-421 |
Number of pages | 7 |
Journal | Protein and Peptide Letters |
Volume | 11 |
Issue number | 5 |
DOIs | |
State | Published - Oct 2004 |
Externally published | Yes |
Keywords
- Endopeptidase
- Exocytosis
- Fusion pore
- Neurolysin
- Peptide metabolism
- Thimet- oligopeptidase
- Unconventional secretion
ASJC Scopus subject areas
- Structural Biology
- Biochemistry