The interaction between mitochondria and oncoviruses

Shujie Song, Shasha Gong, Pragya Singh, Jianxin Lyu, Yidong Bai

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Mitochondria play important roles in multiple aspects of viral tumorigenesis. Mitochondrial genomes contribute to the host's genetic background. After viruses enter the cell, they modulate mitochondrial function and thus alter bioenergetics and retrograde signaling pathways. At the same time, mitochondria also regulate and mediate viral oncogenesis. In this context, oncogenesis by oncoviruses like Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human papilloma virus (HPV), Human Immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) will be discussed.

Original languageEnglish (US)
Pages (from-to)481-487
Number of pages7
JournalBiochimica et Biophysica Acta - Molecular Basis of Disease
Volume1864
Issue number2
DOIs
StatePublished - Feb 2018

Keywords

  • EBV
  • HBV
  • HCV
  • HIV
  • HPV
  • Mitochondria
  • Oncovirus

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology

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