The influence of pineal activation, removal or denervation on hypothalamic luteinizing hormone-releasing hormone activity: An in vitro study

David E. Blask; Russel J. Reiter; Linda Y Johnson

doi:10.1016/0304-3940(75)90021-X

The influence of pineal activation, removal or denervation on hypothalamic luteinizing hormone-releasing hormone activity: An in vitro study

David E. Blask, Russel J. Reiter, Linda Y Johnson

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Female rats between 23 and 25 days of age were left intact or rendered either blind-anosmic, blind-anosmic-pinealectomized, blind-anosmic-superior cervical ganglionectomized or blind-anosmic-nervi conarii transected. Five weeks later the medial basal hypothalamic luteinizing hormone-releasing hormone (LRH) activity of each group of animals was assessed in vitro. The medial basal hypothalamic LRH activity in the blind-anosmic animals was greater than that of the intact rats. Pinealectomy, superior cervical ganglionectomy and nervi conarii transection were equally effective in reversing the effects of blinding and anosmia on LRH activity.

Original language	English (US)
Pages (from-to)	327-332
Number of pages	6
Journal	Neuroscience Letters
Volume	1
Issue number	6
DOIs	https://doi.org/10.1016/0304-3940(75)90021-X
State	Published - Dec 1975

ASJC Scopus subject areas

General Neuroscience

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10.1016/0304-3940(75)90021-X

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@article{107b721e27d149b08efc18423bdd55a4,

title = "The influence of pineal activation, removal or denervation on hypothalamic luteinizing hormone-releasing hormone activity: An in vitro study",

abstract = "Female rats between 23 and 25 days of age were left intact or rendered either blind-anosmic, blind-anosmic-pinealectomized, blind-anosmic-superior cervical ganglionectomized or blind-anosmic-nervi conarii transected. Five weeks later the medial basal hypothalamic luteinizing hormone-releasing hormone (LRH) activity of each group of animals was assessed in vitro. The medial basal hypothalamic LRH activity in the blind-anosmic animals was greater than that of the intact rats. Pinealectomy, superior cervical ganglionectomy and nervi conarii transection were equally effective in reversing the effects of blinding and anosmia on LRH activity.",

author = "Blask, {David E.} and Reiter, {Russel J.} and Johnson, {Linda Y}",

note = "Funding Information: The authors wish to thank the National Institute of Arthritis, Metabolism and Digestive Diseases Rat Pituitary Hormone Distribution Program, for supplying the reagents for the radioimmunoassay. This work was supported by NSF Grant GB-43233X. R.J. Reiter is a U.S.P.H.S. Career Development Awardee, HD-42398.",

year = "1975",

month = dec,

doi = "10.1016/0304-3940(75)90021-X",

language = "English (US)",

volume = "1",

pages = "327--332",

journal = "Neuroscience Letters",

issn = "0304-3940",

publisher = "Elsevier Ireland Ltd",

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TY - JOUR

T1 - The influence of pineal activation, removal or denervation on hypothalamic luteinizing hormone-releasing hormone activity

T2 - An in vitro study

AU - Blask, David E.

AU - Reiter, Russel J.

AU - Johnson, Linda Y

N1 - Funding Information: The authors wish to thank the National Institute of Arthritis, Metabolism and Digestive Diseases Rat Pituitary Hormone Distribution Program, for supplying the reagents for the radioimmunoassay. This work was supported by NSF Grant GB-43233X. R.J. Reiter is a U.S.P.H.S. Career Development Awardee, HD-42398.

PY - 1975/12

Y1 - 1975/12

N2 - Female rats between 23 and 25 days of age were left intact or rendered either blind-anosmic, blind-anosmic-pinealectomized, blind-anosmic-superior cervical ganglionectomized or blind-anosmic-nervi conarii transected. Five weeks later the medial basal hypothalamic luteinizing hormone-releasing hormone (LRH) activity of each group of animals was assessed in vitro. The medial basal hypothalamic LRH activity in the blind-anosmic animals was greater than that of the intact rats. Pinealectomy, superior cervical ganglionectomy and nervi conarii transection were equally effective in reversing the effects of blinding and anosmia on LRH activity.

AB - Female rats between 23 and 25 days of age were left intact or rendered either blind-anosmic, blind-anosmic-pinealectomized, blind-anosmic-superior cervical ganglionectomized or blind-anosmic-nervi conarii transected. Five weeks later the medial basal hypothalamic luteinizing hormone-releasing hormone (LRH) activity of each group of animals was assessed in vitro. The medial basal hypothalamic LRH activity in the blind-anosmic animals was greater than that of the intact rats. Pinealectomy, superior cervical ganglionectomy and nervi conarii transection were equally effective in reversing the effects of blinding and anosmia on LRH activity.

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The influence of pineal activation, removal or denervation on hypothalamic luteinizing hormone-releasing hormone activity: An in vitro study

Abstract

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