TY - JOUR
T1 - The Incredible Elastic Brain
T2 - How Neural Stem Cells Expand Our Minds
AU - Kokovay, Erzsebet
AU - Shen, Qin
AU - Temple, Sally
N1 - Funding Information:
Our sincere thanks to the NSC community of researchers, and apologies for all the papers we could not cite due to space restrictions. EK, QS and ST receive support from NINDS, NYS, the Foundation to Cure Paralysis and the Regenerative Research Foundation.
PY - 2008/11/6
Y1 - 2008/11/6
N2 - Brain development was thought to be largely hardwired and accomplished by birth, and the brain was thought to have essentially no regenerative capacity. The remarkable discovery of adult neurogenesis and neural stem cells (NSCs) existing in the mature CNS changed that, allowing us to think optimistically about CNS repair. These discoveries helped to generate a robust field of neural progenitor cell biology, with relevance to CNS development, pathogenesis, the search for novel neurological therapies, as well as our understanding of how the brain works.
AB - Brain development was thought to be largely hardwired and accomplished by birth, and the brain was thought to have essentially no regenerative capacity. The remarkable discovery of adult neurogenesis and neural stem cells (NSCs) existing in the mature CNS changed that, allowing us to think optimistically about CNS repair. These discoveries helped to generate a robust field of neural progenitor cell biology, with relevance to CNS development, pathogenesis, the search for novel neurological therapies, as well as our understanding of how the brain works.
UR - http://www.scopus.com/inward/record.url?scp=55049100009&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=55049100009&partnerID=8YFLogxK
U2 - 10.1016/j.neuron.2008.10.025
DO - 10.1016/j.neuron.2008.10.025
M3 - Review article
C2 - 18995816
AN - SCOPUS:55049100009
SN - 0896-6273
VL - 60
SP - 420
EP - 429
JO - Neuron
JF - Neuron
IS - 3
ER -