Polycystic ovary syndrome is one of the most common endocrine disorders in women, affecting up to 7% of women of reproductive age. It is characterized by chronic anovulation, hyperandrogenemia, and often obesity . Key reproductive features of PCOS are disordered gonadotropin secretion , elevated ovarian and adrenal androgen production , and frequently polycystic ovaries. Women with PCOS have profound insulin resistance as well as beta cell dysfunction, regardless of obesity and glucose tolerance status .
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