The Effects of Methylmethacrylate's Hyperthermic Polymerization on Cerebral Vascular Permeability

D. F. Jimenez, C. M. Barone, T. Tigno, X. F. Yang, A. Clapper

Research output: Contribution to journalArticle

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This study was undertaken to analyze the effects of significant hyperthermia (> 100°C) associated with the polymerization of polymethlymethacrylate (PMM) on the permeability of the cerebral vasculature in rats. The method used to visualize the pial vasculature included the open pial window technique and epifluorescence microscopy. Results indicated that there is a significant increase in cerebral vascular permeability following in situ polymerization of PMM over the craniectomy site.

Original languageEnglish (US)
Pages (from-to)254-256
Number of pages3
JournalActa Neurochirurgica, Supplement
Issue number70
Publication statusPublished - Jan 1 1997



  • Cerebral vascular permeability
  • Cranioplasty
  • Fluorescence isothiocyanate (FITC) albumin
  • Hyperthermia
  • Polymethylmethacrylate

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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