The effects of diabetes mellitus on the material properties of human metatarsal bones

John G. Fleischli, Terese J. Laughlin, Lawrence A. Lavery, Bhavesh Shah, Dan Lanctot, C. Mauli Agrawal, Kyriakos Athanasiou

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

While some investigations have focused on the effect of diabetes on the material properties of connective tissue in both the human and animal model, no study to date has investigated the effects of the disease process on human metatarsal bones. This investigation compared the material properties of human metatarsal bones from young diabetic donors (51.3 ± 8 years) and older nondiabetic donors (72.3 ± 10 years). The results demonstrated no significant differences between the two groups. This would seem to suggest that the effects of aging are comparable to the effects of diabetes on the structural integrity of human metatarsal bones.

Original languageEnglish (US)
Pages (from-to)195-198
Number of pages4
JournalJournal of Foot and Ankle Surgery
Volume37
Issue number3
DOIs
StatePublished - 1998

Keywords

  • Bone
  • Diabetes mellitus
  • Elastic modulus
  • Fracture
  • Material properties of bone
  • Metatarsal

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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    Fleischli, J. G., Laughlin, T. J., Lavery, L. A., Shah, B., Lanctot, D., Agrawal, C. M., & Athanasiou, K. (1998). The effects of diabetes mellitus on the material properties of human metatarsal bones. Journal of Foot and Ankle Surgery, 37(3), 195-198. https://doi.org/10.1016/S1067-2516(98)80110-5