TY - JOUR
T1 - The effects of BleedArrest on hemorrhage control in a porcine model.
AU - Gegel, Brian
AU - Burgert, James
AU - Loughren, Michael
AU - Johnson, Don
PY - 2012/1/1
Y1 - 2012/1/1
N2 - The purpose of this study was to examine the effectiveness of the hemostatic agent BleedArrest compared to control. This was a prospective, experimental design employing an established porcine model of uncontrolled hemorrhage. The minimum number of animals (n=10 per group) was used to obtain a statistically valid result. There were no statistically significant differences between the groups (P>.05) indicating that the groups were equivalent on the following parameters: activating clotting time, the subject weights, core body temperatures, amount of one minute hemorrhage, arterial blood pressures, and the amount and percentage of total blood volume. There were significant differences in the amount of hemorrhage (P=.033) between the BleedArrest (mean=72, SD±72 mL) and control (mean=317.30, SD±112.02 mL). BleedArrest is statistically and clinically superior at controlling hemorrhage compared to the standard pressure dressing control group. In conclusion, BleedArrest is an effective hemostatic agent for use in civilian and military trauma management.
AB - The purpose of this study was to examine the effectiveness of the hemostatic agent BleedArrest compared to control. This was a prospective, experimental design employing an established porcine model of uncontrolled hemorrhage. The minimum number of animals (n=10 per group) was used to obtain a statistically valid result. There were no statistically significant differences between the groups (P>.05) indicating that the groups were equivalent on the following parameters: activating clotting time, the subject weights, core body temperatures, amount of one minute hemorrhage, arterial blood pressures, and the amount and percentage of total blood volume. There were significant differences in the amount of hemorrhage (P=.033) between the BleedArrest (mean=72, SD±72 mL) and control (mean=317.30, SD±112.02 mL). BleedArrest is statistically and clinically superior at controlling hemorrhage compared to the standard pressure dressing control group. In conclusion, BleedArrest is an effective hemostatic agent for use in civilian and military trauma management.
UR - http://www.scopus.com/inward/record.url?scp=84871885978&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871885978&partnerID=8YFLogxK
M3 - Article
C2 - 23007934
AN - SCOPUS:84871885978
SP - 31
EP - 35
JO - U.S. Army Medical Department journal
JF - U.S. Army Medical Department journal
SN - 1524-0436
ER -