The effect of myometrial contractures on uterine blood flow in the pregnant sheep at 114 to 140 days' gestation measured by the 4-aminoantipyrine equilibrium diffusion technique

S. G. Sunderji, A. El Badry, E. R. Poore, J. P. Figueroa, P. W. Nathanielsz

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Uterine blood flow, between 114 and 140 days' gestation, measured by the 4-aminoantipyrine equilibrium diffusion technique, was significantly decreased from 1359.1 ± 84.4 ml · min-1 (mean ± SE) in the absence of contractures to 1147.4 ± 71.8 ml · min-1 (mean ± SE) during a contracture (p < 0.01). Contractures reduced total uterine blood flow regardless of whether the ewe was standing or lying. These observations are in keeping with the suggestion that changes in total uterine blood flow may be an important mechanism responsible for the previously described temporal relationship between contractures and fetal neurophysiologic function.

Original languageEnglish (US)
Pages (from-to)408-412
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume149
Issue number4
DOIs
StatePublished - Jun 15 1984
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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