The Effect of Hypothermia on Experimentally Induced Hemorrhagic Pancreatic Necrosis

Conrad B. Jenson, Kamil Imamoglu, Harlan D. Root, Owen H. Wangensteen

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Pancreatic secretion in the dog following pilocarpine stimulation was markedly reduced by pancreatic hypothermia (15° to 23° C.) The mortality rate for pancreatic necrosis evoked by injection of bile salts or duodenal juice into the pancreatic duct, or by the Shwartzman reaction, was enhanced slightly by use of systemic (25° to 30° C.) or local (15° to 23° C.) hypothermia. Permeability of the cat esophagus to perfused human bile enriched with ox bile salts was not significantly altered by hypothermia (18° to 20° C).

Original languageEnglish (US)
Pages (from-to)532-535
Number of pages4
JournalGastroenterology
Volume40
Issue number4
DOIs
StatePublished - 1961
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

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