The effect of carotid artery disease on the cerebrovascular response to physiologic stimulation

W. J. Powers, Peter T Fox, M. E. Raichle

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Eight of 16 patients with severe carotid artery disease, but no evidence of functional or structural brain damage, had abnormal regional cerebral blood flow (rCBF) responses to physiologic stimulation of sensorimotor cortex (unilateral reduction in six, abnormal diffuse increase in two). Thus, in patients with cerebrovascular disease the rCBF responses during physiologic tasks may not be reliable indicators of local neuronal activity.

Original languageEnglish (US)
Pages (from-to)1475-1478
Number of pages4
JournalNeurology
Volume38
Issue number9
StatePublished - 1988
Externally publishedYes

Fingerprint

Cerebrovascular Circulation
Carotid Artery Diseases
Regional Blood Flow
Cerebrovascular Disorders
Brain

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The effect of carotid artery disease on the cerebrovascular response to physiologic stimulation. / Powers, W. J.; Fox, Peter T; Raichle, M. E.

In: Neurology, Vol. 38, No. 9, 1988, p. 1475-1478.

Research output: Contribution to journalArticle

@article{11a4930128c14fadbcd5cac840d3bf10,
title = "The effect of carotid artery disease on the cerebrovascular response to physiologic stimulation",
abstract = "Eight of 16 patients with severe carotid artery disease, but no evidence of functional or structural brain damage, had abnormal regional cerebral blood flow (rCBF) responses to physiologic stimulation of sensorimotor cortex (unilateral reduction in six, abnormal diffuse increase in two). Thus, in patients with cerebrovascular disease the rCBF responses during physiologic tasks may not be reliable indicators of local neuronal activity.",
author = "Powers, {W. J.} and Fox, {Peter T} and Raichle, {M. E.}",
year = "1988",
language = "English (US)",
volume = "38",
pages = "1475--1478",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - The effect of carotid artery disease on the cerebrovascular response to physiologic stimulation

AU - Powers, W. J.

AU - Fox, Peter T

AU - Raichle, M. E.

PY - 1988

Y1 - 1988

N2 - Eight of 16 patients with severe carotid artery disease, but no evidence of functional or structural brain damage, had abnormal regional cerebral blood flow (rCBF) responses to physiologic stimulation of sensorimotor cortex (unilateral reduction in six, abnormal diffuse increase in two). Thus, in patients with cerebrovascular disease the rCBF responses during physiologic tasks may not be reliable indicators of local neuronal activity.

AB - Eight of 16 patients with severe carotid artery disease, but no evidence of functional or structural brain damage, had abnormal regional cerebral blood flow (rCBF) responses to physiologic stimulation of sensorimotor cortex (unilateral reduction in six, abnormal diffuse increase in two). Thus, in patients with cerebrovascular disease the rCBF responses during physiologic tasks may not be reliable indicators of local neuronal activity.

UR - http://www.scopus.com/inward/record.url?scp=0023741023&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023741023&partnerID=8YFLogxK

M3 - Article

VL - 38

SP - 1475

EP - 1478

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 9

ER -