The dangers of using single locus markers in parasite epidemiology: Ascaris as a case study

Tim J.C. Anderson

    Research output: Contribution to journalReview article

    97 Scopus citations

    Abstract

    Molecular markers are used widely to discriminate between closely related species of parasites, and in many cases a single locus is used for this purpose. This article aims to show how molecular data derived from a single genetic marker or linkage group - in this case mitochondrial DNA - can lead to ambiguous conclusions and to illustrate how a multilocus approach has enhanced our understanding of the epidemiology of two closely related parasites, the nematodes Ascaris suum, which infects pigs, and Ascaris lumbicoides, which infects humans.

    Original languageEnglish (US)
    Pages (from-to)183-188
    Number of pages6
    JournalTrends in Parasitology
    Volume17
    Issue number4
    DOIs
    StatePublished - Apr 1 2001

    ASJC Scopus subject areas

    • Parasitology
    • Infectious Diseases

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