TY - JOUR
T1 - The dangers of using single locus markers in parasite epidemiology
T2 - Ascaris as a case study
AU - Anderson, Tim J.C.
PY - 2001/4/1
Y1 - 2001/4/1
N2 - Molecular markers are used widely to discriminate between closely related species of parasites, and in many cases a single locus is used for this purpose. This article aims to show how molecular data derived from a single genetic marker or linkage group - in this case mitochondrial DNA - can lead to ambiguous conclusions and to illustrate how a multilocus approach has enhanced our understanding of the epidemiology of two closely related parasites, the nematodes Ascaris suum, which infects pigs, and Ascaris lumbicoides, which infects humans.
AB - Molecular markers are used widely to discriminate between closely related species of parasites, and in many cases a single locus is used for this purpose. This article aims to show how molecular data derived from a single genetic marker or linkage group - in this case mitochondrial DNA - can lead to ambiguous conclusions and to illustrate how a multilocus approach has enhanced our understanding of the epidemiology of two closely related parasites, the nematodes Ascaris suum, which infects pigs, and Ascaris lumbicoides, which infects humans.
UR - http://www.scopus.com/inward/record.url?scp=0035303574&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035303574&partnerID=8YFLogxK
U2 - 10.1016/S1471-4922(00)01944-9
DO - 10.1016/S1471-4922(00)01944-9
M3 - Review article
C2 - 11282508
AN - SCOPUS:0035303574
VL - 17
SP - 183
EP - 188
JO - Trends in Parasitology
JF - Trends in Parasitology
SN - 1471-4922
IS - 4
ER -