The dangers of using single locus markers in parasite epidemiology: Ascaris as a case study

Tim J.C. Anderson

doi:10.1016/S1471-4922(00)01944-9

The dangers of using single locus markers in parasite epidemiology: Ascaris as a case study

Tim J.C. Anderson

Research output: Contribution to journal › Review article › peer-review

100 Scopus citations

Abstract

Molecular markers are used widely to discriminate between closely related species of parasites, and in many cases a single locus is used for this purpose. This article aims to show how molecular data derived from a single genetic marker or linkage group - in this case mitochondrial DNA - can lead to ambiguous conclusions and to illustrate how a multilocus approach has enhanced our understanding of the epidemiology of two closely related parasites, the nematodes Ascaris suum, which infects pigs, and Ascaris lumbicoides, which infects humans.

Original language	English (US)
Pages (from-to)	183-188
Number of pages	6
Journal	Trends in Parasitology
Volume	17
Issue number	4
DOIs	https://doi.org/10.1016/S1471-4922(00)01944-9
State	Published - Apr 1 2001

ASJC Scopus subject areas

Parasitology
Infectious Diseases

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