The Daily Activity Report (DAR) a novel measure of functional outcome for serious mental illness

Dawn I. Velligan, Jim Mintz, Cynthia Sierra, Mona L. Martin, Megan Fredrick, Gregory A. Maglinte, Patricia K. Corey-Lisle

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The assessment of real-world functional outcomes in clinical trials for medications targeting negative symptoms and cognitive impairment is extremely important. We tested the psychometric properties of the Daily Activity Report (DAR), a novel assessment of productive daily activity. We administered the DAR and additional assessments of functional outcome, functional capacity, cognition and symptomatology to 50 individuals with schizophrenia at 2 time points, 1 month apart and to 25 healthy controls. The DAR records a person's daily activity for 7 consecutive days based upon phone calls made 3 times a day. A total score and scores in 3 domains; instrumental activities (ie, independent living), social and work or school related activities are generated for the DAR. Inter-item consistency was high 0.89-0.94 for each domain and 0.88 overall. Test-retest reliability across 1 month for the total DAR score was 0.67, P <. 0001. The total DAR score as well as scores for social activity and nondomestic work/school differed significantly between control and patient participants (P <. 0001). DAR domain scores were associated with negative symptoms and functional outcomes, but the primary score related to these measures was the work/school dimension of the DAR. DAR scores were only weakly and nonsignificantly related to positive symptoms. This study provides preliminary support for the reliability and validity of the DAR using interviewer administration. The development of a patient reported version of the DAR using smart phone technology with automatic scoring is the next step.

Original languageEnglish (US)
Pages (from-to)579-587
Number of pages9
JournalSchizophrenia bulletin
Volume42
Issue number3
DOIs
StatePublished - May 1 2016

Keywords

  • functional outcome
  • realworld outcomes
  • schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'The Daily Activity Report (DAR) a novel measure of functional outcome for serious mental illness'. Together they form a unique fingerprint.

  • Cite this