The complex world of kidney microRNAs

Balakuntalam S. Kasinath, Denis Feliers

Research output: Contribution to journalComment/debatepeer-review

27 Scopus citations

Abstract

MicroRNAs are short noncoding RNAs that usually reduce translation of messenger RNAs. Changes in microRNA-192 (miR-192) are reported in states of renal fibrosis. New evidence supports a role for miR-192 and its target miR-200b/c in transforming growth factor-Β1 regulation of its own expression and that of collagens in mesangial cells, with a possible role in diabetic nephropathy. As there is controversy on the role of these microRNAs in diabetic nephropathy, more work is needed.

Original languageEnglish (US)
Pages (from-to)334-337
Number of pages4
JournalKidney international
Volume80
Issue number4
DOIs
StatePublished - Aug 2 2011

ASJC Scopus subject areas

  • Nephrology

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