The cholinergic system in rat striatum during morphine tolerance and dependence

A. Schurr; B. M. Rigor; R. Strong; Z. Gottesfeld

doi:10.1016/0024-3205(83)90161-3

The cholinergic system in rat striatum during morphine tolerance and dependence

A. Schurr, B. M. Rigor, R. Strong, Z. Gottesfeld

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Male Sprague-Dawley rats were used in the present study to assess the effects of chronic treatment of morphine on the striatal cholinergic system. The results demonstrate that neither short nor long-term morphine treatment had an effect on choline acetyltransferase (ChAT) activity or ³H- quinuclidinylbenzilate (³HQNB) binding in discrete striatal regions of the rat brain.

Original language	English (US)
Pages (from-to)	2521-2525
Number of pages	5
Journal	Life Sciences
Volume	33
Issue number	25
DOIs	https://doi.org/10.1016/0024-3205(83)90161-3
State	Published - Dec 19 1983
Externally published	Yes

ASJC Scopus subject areas

General Pharmacology, Toxicology and Pharmaceutics
General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1016/0024-3205(83)90161-3

Cite this

@article{cdc286c4e1774bc8bbb85ffa08bd1f0e,

title = "The cholinergic system in rat striatum during morphine tolerance and dependence",

abstract = "Male Sprague-Dawley rats were used in the present study to assess the effects of chronic treatment of morphine on the striatal cholinergic system. The results demonstrate that neither short nor long-term morphine treatment had an effect on choline acetyltransferase (ChAT) activity or 3H- quinuclidinylbenzilate (3HQNB) binding in discrete striatal regions of the rat brain.",

author = "A. Schurr and Rigor, {B. M.} and R. Strong and Z. Gottesfeld",

year = "1983",

month = dec,

day = "19",

doi = "10.1016/0024-3205(83)90161-3",

language = "English (US)",

volume = "33",

pages = "2521--2525",

journal = "Life Sciences",

issn = "0024-3205",

publisher = "Elsevier Inc.",

number = "25",

}

TY - JOUR

T1 - The cholinergic system in rat striatum during morphine tolerance and dependence

AU - Schurr, A.

AU - Rigor, B. M.

AU - Strong, R.

AU - Gottesfeld, Z.

PY - 1983/12/19

Y1 - 1983/12/19

N2 - Male Sprague-Dawley rats were used in the present study to assess the effects of chronic treatment of morphine on the striatal cholinergic system. The results demonstrate that neither short nor long-term morphine treatment had an effect on choline acetyltransferase (ChAT) activity or 3H- quinuclidinylbenzilate (3HQNB) binding in discrete striatal regions of the rat brain.

AB - Male Sprague-Dawley rats were used in the present study to assess the effects of chronic treatment of morphine on the striatal cholinergic system. The results demonstrate that neither short nor long-term morphine treatment had an effect on choline acetyltransferase (ChAT) activity or 3H- quinuclidinylbenzilate (3HQNB) binding in discrete striatal regions of the rat brain.

UR - http://www.scopus.com/inward/record.url?scp=0021080190&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021080190&partnerID=8YFLogxK

U2 - 10.1016/0024-3205(83)90161-3

DO - 10.1016/0024-3205(83)90161-3

M3 - Article

C2 - 6685808

AN - SCOPUS:0021080190

SN - 0024-3205

VL - 33

SP - 2521

EP - 2525

JO - Life Sciences

JF - Life Sciences

IS - 25

ER -

The cholinergic system in rat striatum during morphine tolerance and dependence

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this