The cancer genome atlas pan-cancer analysis project

John N. Weinstein, Eric A. Collisson, Gordon B. Mills, Kenna R.Mills Shaw, Brad A. Ozenberger, Kyle Ellrott, Chris Sander, Joshua M. Stuart, Kyle Chang, Chad J. Creighton, Caleb Davis, Lawrence Donehower, Jennifer Drummond, David Wheeler, Adrian Ally, Miruna Balasundaram, Inanc Birol, Yaron S.N. Butterfield, Andy Chu, Eric Chuah & 316 others Hye Jung E. Chun, Noreen Dhalla, Ranabir Guin, Martin Hirst, Carrie Hirst, Robert A. Holt, Steven J.M. Jones, Darlene Lee, Haiyan I. Li, Marco A. Marra, Michael Mayo, Richard A. Moore, Andrew J. Mungall, A. Gordon Robertson, Jacqueline E. Schein, Payal Sipahimalani, Angela Tam, Nina Thiessen, Richard J. Varhol, Rameen Beroukhim, Ami S. Bhatt, Angela N. Brooks, Andrew D. Cherniack, Samuel S. Freeman, Stacey B. Gabriel, Elena Helman, Joonil Jung, Matthew Meyerson, Akinyemi I. Ojesina, Chandra Sekhar Pedamallu, Gordon Saksena, Steven E. Schumacher, Barbara Tabak, Travis Zack, Eric S. Lander, Christopher A. Bristow, Angela Hadjipanayis, Psalm Haseley, Raju Kucherlapati, Semin Lee, Eunjung Lee, Lovelace J. Luquette, Harshad S. Mahadeshwar, Angeliki Pantazi, Michael Parfenov, Peter J. Park, Alexei Protopopov, Xiaojia Ren, Netty Santoso, Jonathan Seidman, Sahil Seth, Xingzhi Song, Jiabin Tang, Ruibin Xi, Andrew W. Xu, Lixing Yang, Dong Zeng, J. Todd Auman, Saianand Balu, Elizabeth Buda, Cheng Fan, Katherine A. Hoadley, Corbin D. Jones, Shaowu Meng, Piotr A. Mieczkowski, Joel S. Parker, Charles M. Perou, Jeffrey Roach, Yan Shi, Grace O. Silva, Donghui Tan, Umadevi Veluvolu, Scot Waring, Matthew D. Wilkerson, Junyuan Wu, Wei Zhao, Tom Bodenheimer, D. Neil Hayes, Alan P. Hoyle, Stuart R. Jeffreys, Lisle E. Mose, Janae V. Simons, Mathew G. Soloway, Stephen B. Baylin, Benjamin P. Berman, Moiz S. Bootwalla, Ludmila Danilova, James G. Herman, Toshinori Hinoue, Peter W. Laird, Suhn K. Rhie, Hui Shen, Timothy Triche, Daniel J. Weisenberger, Scott L. Carter, Kristian Cibulskis, Lynda Chin, Jianhua Zhang, Carrie Sougnez, Min Wang, Gad Getz, Huyen Dinh, Harsha Vardhan Doddapaneni, Richard Gibbs, Preethi Gunaratne, Yi Han, Divya Kalra, Christie Kovar, Lora Lewis, Margaret Morgan, Donna Morton, Donna Muzny, Jeffrey Reid, Liu Xi, Juok Cho, Daniel Dicara, Scott Frazer, Nils Gehlenborg, David I. Heiman, Jaegil Kim, Michael S. Lawrence, Pei Lin, Yingchun Liu, Michael S. Noble, Petar Stojanov, Doug Voet, Hailei Zhang, Lihua Zou, Chip Stewart, Brady Bernard, Ryan Bressler, Andrea Eakin, Lisa Iype, Theo Knijnenburg, Roger Kramer, Richard Kreisberg, Kalle Leinonen, Jake Lin, Yuexin Liu, Michael Miller, Sheila M. Reynolds, Hector Rovira, Ilya Shmulevich, Vesteinn Thorsson, Da Yang, Wei Zhang, Samirkumar Amin, Chang Jiun Wu, Chia Chin Wu, Rehan Akbani, Kenneth Aldape, Keith A. Baggerly, Bradley Broom, Tod D. Casasent, James Cleland, Deepti Dodda, Mary Edgerton, Leng Han, Shelley M. Herbrich, Zhenlin Ju, Hoon Kim, Seth Lerner, Jun Li, Han Liang, Wenbin Liu, Philip L. Lorenzi, Yiling Lu, James Melott, Lam Nguyen, Xiaoping Su, Roeland Verhaak, Wenyi Wang, Andrew Wong, Yang Yang, Jun Yao, Rong Yao, Kosuke Yoshihara, Yuan Yuan, Alfred K. Yung, Nianxiang Zhang, Siyuan Zheng, Michael Ryan, David W. Kane, B. Arman Aksoy, Giovanni Ciriello, Gideon Dresdner, Jianjiong Gao, Benjamin Gross, Anders Jacobsen, Andre Kahles, Marc Ladanyi, William Lee, Kjong Van Lehmann, Martin L. Miller, Ricardo Ramirez, Gunnar Rätsch, Boris Reva, Nikolaus Schultz, Yasin Senbabaoglu, Ronglai Shen, Rileen Sinha, S. Onur Sumer, Yichao Sun, Barry S. Taylor, Nils Weinhold, Suzanne Fei, Paul Spellman, Christopher Benz, Daniel Carlin, Melisssa Cline, Brian Craft, Mary Goldman, David Haussler, Singer Ma, Sam Ng, Evan Paull, Amie Radenbaugh, Sofie Salama, Artem Sokolov, Teresa Swatloski, Vladislav Uzunangelov, Peter Waltman, Christina Yau, Jing Zhu, Stanley R. Hamilton, Scott Abbott, Rachel Abbott, Nathan D. Dees, Kim Delehaunty, Li Ding, David J. Dooling, Jim M. Eldred, Catrina C. Fronick, Robert Fulton, Lucinda L. Fulton, Joelle Kalicki-Veizer, Krishna Latha Kanchi, Cyriac Kandoth, Daniel C. Koboldt, David E. Larson, Timothy J. Ley, Ling Lin, Charles Lu, Vincent J. Magrini, Elaine R. Mardis, Michael D. McLellan, Joshua F. McMichael, Christopher A. Miller, Michelle O'Laughlin, Craig Pohl, Heather Schmidt, Scott M. Smith, Jason Walker, John W. Wallis, Michael C. Wendl, Richard K. Wilson, Todd Wylie, Qunyuan Zhang, Robert Burton, Mark A. Jensen, Ari Kahn, Todd Pihl, David Pot, Yunhu Wan, Douglas A. Levine, Aaron D. Black, Jay Bowen, Jessica Frick, Julie M. Gastier-Foster, Hollie A. Harper, Carmen Helsel, Kristen M. Leraas, Tara M. Lichtenberg, Cynthia McAllister, Nilsa C. Ramirez, Samantha Sharpe, Lisa Wise, Erik Zmuda, Stephen J. Chanock, Tanja Davidsen, John A. Demchok, Greg Eley, Ina Felau, Margi Sheth, Heidi Sofia, Louis Staudt, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jiashan Zhang, Larsson Omberg, Adam Margolin, Benjamin J. Raphael, Fabio Vandin, Hsin Ta Wu, Mark D.M. Leiserson, Stephen C. Benz, Charles J. Vaske, Houtan Noushmehr, Denise Wolf, Laura Van T. Veer, Dimitris Anastassiou, Tai Hsien Ou Yang, Nuria Lopez-Bigas, Abel Gonzalez-Perez, David Tamborero, Zheng Xia, Wei Li, Dong Yeon Cho, Teresa Przytycka, Mark Hamilton, Sean McGuire, Sven Nelander, Patrik Johansson, Rebecka Jörnsten, Teresia Kling

Research output: Contribution to journalReview article

1727 Citations (Scopus)

Abstract

The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile.

Original languageEnglish (US)
Pages (from-to)1113-1120
Number of pages8
JournalNature Genetics
Volume45
Issue number10
DOIs
StatePublished - Oct 1 2013
Externally publishedYes

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Atlases
Genome
Neoplasms
Epigenomics
RNA
DNA
Research

ASJC Scopus subject areas

  • Genetics

Cite this

Weinstein, J. N., Collisson, E. A., Mills, G. B., Shaw, K. R. M., Ozenberger, B. A., Ellrott, K., ... Kling, T. (2013). The cancer genome atlas pan-cancer analysis project. Nature Genetics, 45(10), 1113-1120. https://doi.org/10.1038/ng.2764

The cancer genome atlas pan-cancer analysis project. / Weinstein, John N.; Collisson, Eric A.; Mills, Gordon B.; Shaw, Kenna R.Mills; Ozenberger, Brad A.; Ellrott, Kyle; Sander, Chris; Stuart, Joshua M.; Chang, Kyle; Creighton, Chad J.; Davis, Caleb; Donehower, Lawrence; Drummond, Jennifer; Wheeler, David; Ally, Adrian; Balasundaram, Miruna; Birol, Inanc; Butterfield, Yaron S.N.; Chu, Andy; Chuah, Eric; Chun, Hye Jung E.; Dhalla, Noreen; Guin, Ranabir; Hirst, Martin; Hirst, Carrie; Holt, Robert A.; Jones, Steven J.M.; Lee, Darlene; Li, Haiyan I.; Marra, Marco A.; Mayo, Michael; Moore, Richard A.; Mungall, Andrew J.; Robertson, A. Gordon; Schein, Jacqueline E.; Sipahimalani, Payal; Tam, Angela; Thiessen, Nina; Varhol, Richard J.; Beroukhim, Rameen; Bhatt, Ami S.; Brooks, Angela N.; Cherniack, Andrew D.; Freeman, Samuel S.; Gabriel, Stacey B.; Helman, Elena; Jung, Joonil; Meyerson, Matthew; Ojesina, Akinyemi I.; Pedamallu, Chandra Sekhar; Saksena, Gordon; Schumacher, Steven E.; Tabak, Barbara; Zack, Travis; Lander, Eric S.; Bristow, Christopher A.; Hadjipanayis, Angela; Haseley, Psalm; Kucherlapati, Raju; Lee, Semin; Lee, Eunjung; Luquette, Lovelace J.; Mahadeshwar, Harshad S.; Pantazi, Angeliki; Parfenov, Michael; Park, Peter J.; Protopopov, Alexei; Ren, Xiaojia; Santoso, Netty; Seidman, Jonathan; Seth, Sahil; Song, Xingzhi; Tang, Jiabin; Xi, Ruibin; Xu, Andrew W.; Yang, Lixing; Zeng, Dong; Auman, J. Todd; Balu, Saianand; Buda, Elizabeth; Fan, Cheng; Hoadley, Katherine A.; Jones, Corbin D.; Meng, Shaowu; Mieczkowski, Piotr A.; Parker, Joel S.; Perou, Charles M.; Roach, Jeffrey; Shi, Yan; Silva, Grace O.; Tan, Donghui; Veluvolu, Umadevi; Waring, Scot; Wilkerson, Matthew D.; Wu, Junyuan; Zhao, Wei; Bodenheimer, Tom; Hayes, D. Neil; Hoyle, Alan P.; Jeffreys, Stuart R.; Mose, Lisle E.; Simons, Janae V.; Soloway, Mathew G.; Baylin, Stephen B.; Berman, Benjamin P.; Bootwalla, Moiz S.; Danilova, Ludmila; Herman, James G.; Hinoue, Toshinori; Laird, Peter W.; Rhie, Suhn K.; Shen, Hui; Triche, Timothy; Weisenberger, Daniel J.; Carter, Scott L.; Cibulskis, Kristian; Chin, Lynda; Zhang, Jianhua; Sougnez, Carrie; Wang, Min; Getz, Gad; Dinh, Huyen; Doddapaneni, Harsha Vardhan; Gibbs, Richard; Gunaratne, Preethi; Han, Yi; Kalra, Divya; Kovar, Christie; Lewis, Lora; Morgan, Margaret; Morton, Donna; Muzny, Donna; Reid, Jeffrey; Xi, Liu; Cho, Juok; Dicara, Daniel; Frazer, Scott; Gehlenborg, Nils; Heiman, David I.; Kim, Jaegil; Lawrence, Michael S.; Lin, Pei; Liu, Yingchun; Noble, Michael S.; Stojanov, Petar; Voet, Doug; Zhang, Hailei; Zou, Lihua; Stewart, Chip; Bernard, Brady; Bressler, Ryan; Eakin, Andrea; Iype, Lisa; Knijnenburg, Theo; Kramer, Roger; Kreisberg, Richard; Leinonen, Kalle; Lin, Jake; Liu, Yuexin; Miller, Michael; Reynolds, Sheila M.; Rovira, Hector; Shmulevich, Ilya; Thorsson, Vesteinn; Yang, Da; Zhang, Wei; Amin, Samirkumar; Wu, Chang Jiun; Wu, Chia Chin; Akbani, Rehan; Aldape, Kenneth; Baggerly, Keith A.; Broom, Bradley; Casasent, Tod D.; Cleland, James; Dodda, Deepti; Edgerton, Mary; Han, Leng; Herbrich, Shelley M.; Ju, Zhenlin; Kim, Hoon; Lerner, Seth; Li, Jun; Liang, Han; Liu, Wenbin; Lorenzi, Philip L.; Lu, Yiling; Melott, James; Nguyen, Lam; Su, Xiaoping; Verhaak, Roeland; Wang, Wenyi; Wong, Andrew; Yang, Yang; Yao, Jun; Yao, Rong; Yoshihara, Kosuke; Yuan, Yuan; Yung, Alfred K.; Zhang, Nianxiang; Zheng, Siyuan; Ryan, Michael; Kane, David W.; Aksoy, B. Arman; Ciriello, Giovanni; Dresdner, Gideon; Gao, Jianjiong; Gross, Benjamin; Jacobsen, Anders; Kahles, Andre; Ladanyi, Marc; Lee, William; Lehmann, Kjong Van; Miller, Martin L.; Ramirez, Ricardo; Rätsch, Gunnar; Reva, Boris; Schultz, Nikolaus; Senbabaoglu, Yasin; Shen, Ronglai; Sinha, Rileen; Sumer, S. Onur; Sun, Yichao; Taylor, Barry S.; Weinhold, Nils; Fei, Suzanne; Spellman, Paul; Benz, Christopher; Carlin, Daniel; Cline, Melisssa; Craft, Brian; Goldman, Mary; Haussler, David; Ma, Singer; Ng, Sam; Paull, Evan; Radenbaugh, Amie; Salama, Sofie; Sokolov, Artem; Swatloski, Teresa; Uzunangelov, Vladislav; Waltman, Peter; Yau, Christina; Zhu, Jing; Hamilton, Stanley R.; Abbott, Scott; Abbott, Rachel; Dees, Nathan D.; Delehaunty, Kim; Ding, Li; Dooling, David J.; Eldred, Jim M.; Fronick, Catrina C.; Fulton, Robert; Fulton, Lucinda L.; Kalicki-Veizer, Joelle; Kanchi, Krishna Latha; Kandoth, Cyriac; Koboldt, Daniel C.; Larson, David E.; Ley, Timothy J.; Lin, Ling; Lu, Charles; Magrini, Vincent J.; Mardis, Elaine R.; McLellan, Michael D.; McMichael, Joshua F.; Miller, Christopher A.; O'Laughlin, Michelle; Pohl, Craig; Schmidt, Heather; Smith, Scott M.; Walker, Jason; Wallis, John W.; Wendl, Michael C.; Wilson, Richard K.; Wylie, Todd; Zhang, Qunyuan; Burton, Robert; Jensen, Mark A.; Kahn, Ari; Pihl, Todd; Pot, David; Wan, Yunhu; Levine, Douglas A.; Black, Aaron D.; Bowen, Jay; Frick, Jessica; Gastier-Foster, Julie M.; Harper, Hollie A.; Helsel, Carmen; Leraas, Kristen M.; Lichtenberg, Tara M.; McAllister, Cynthia; Ramirez, Nilsa C.; Sharpe, Samantha; Wise, Lisa; Zmuda, Erik; Chanock, Stephen J.; Davidsen, Tanja; Demchok, John A.; Eley, Greg; Felau, Ina; Sheth, Margi; Sofia, Heidi; Staudt, Louis; Tarnuzzer, Roy; Wang, Zhining; Yang, Liming; Zhang, Jiashan; Omberg, Larsson; Margolin, Adam; Raphael, Benjamin J.; Vandin, Fabio; Wu, Hsin Ta; Leiserson, Mark D.M.; Benz, Stephen C.; Vaske, Charles J.; Noushmehr, Houtan; Wolf, Denise; Veer, Laura Van T.; Anastassiou, Dimitris; Yang, Tai Hsien Ou; Lopez-Bigas, Nuria; Gonzalez-Perez, Abel; Tamborero, David; Xia, Zheng; Li, Wei; Cho, Dong Yeon; Przytycka, Teresa; Hamilton, Mark; McGuire, Sean; Nelander, Sven; Johansson, Patrik; Jörnsten, Rebecka; Kling, Teresia.

In: Nature Genetics, Vol. 45, No. 10, 01.10.2013, p. 1113-1120.

Research output: Contribution to journalReview article

Weinstein, JN, Collisson, EA, Mills, GB, Shaw, KRM, Ozenberger, BA, Ellrott, K, Sander, C, Stuart, JM, Chang, K, Creighton, CJ, Davis, C, Donehower, L, Drummond, J, Wheeler, D, Ally, A, Balasundaram, M, Birol, I, Butterfield, YSN, Chu, A, Chuah, E, Chun, HJE, Dhalla, N, Guin, R, Hirst, M, Hirst, C, Holt, RA, Jones, SJM, Lee, D, Li, HI, Marra, MA, Mayo, M, Moore, RA, Mungall, AJ, Robertson, AG, Schein, JE, Sipahimalani, P, Tam, A, Thiessen, N, Varhol, RJ, Beroukhim, R, Bhatt, AS, Brooks, AN, Cherniack, AD, Freeman, SS, Gabriel, SB, Helman, E, Jung, J, Meyerson, M, Ojesina, AI, Pedamallu, CS, Saksena, G, Schumacher, SE, Tabak, B, Zack, T, Lander, ES, Bristow, CA, Hadjipanayis, A, Haseley, P, Kucherlapati, R, Lee, S, Lee, E, Luquette, LJ, Mahadeshwar, HS, Pantazi, A, Parfenov, M, Park, PJ, Protopopov, A, Ren, X, Santoso, N, Seidman, J, Seth, S, Song, X, Tang, J, Xi, R, Xu, AW, Yang, L, Zeng, D, Auman, JT, Balu, S, Buda, E, Fan, C, Hoadley, KA, Jones, CD, Meng, S, Mieczkowski, PA, Parker, JS, Perou, CM, Roach, J, Shi, Y, Silva, GO, Tan, D, Veluvolu, U, Waring, S, Wilkerson, MD, Wu, J, Zhao, W, Bodenheimer, T, Hayes, DN, Hoyle, AP, Jeffreys, SR, Mose, LE, Simons, JV, Soloway, MG, Baylin, SB, Berman, BP, Bootwalla, MS, Danilova, L, Herman, JG, Hinoue, T, Laird, PW, Rhie, SK, Shen, H, Triche, T, Weisenberger, DJ, Carter, SL, Cibulskis, K, Chin, L, Zhang, J, Sougnez, C, Wang, M, Getz, G, Dinh, H, Doddapaneni, HV, Gibbs, R, Gunaratne, P, Han, Y, Kalra, D, Kovar, C, Lewis, L, Morgan, M, Morton, D, Muzny, D, Reid, J, Xi, L, Cho, J, Dicara, D, Frazer, S, Gehlenborg, N, Heiman, DI, Kim, J, Lawrence, MS, Lin, P, Liu, Y, Noble, MS, Stojanov, P, Voet, D, Zhang, H, Zou, L, Stewart, C, Bernard, B, Bressler, R, Eakin, A, Iype, L, Knijnenburg, T, Kramer, R, Kreisberg, R, Leinonen, K, Lin, J, Liu, Y, Miller, M, Reynolds, SM, Rovira, H, Shmulevich, I, Thorsson, V, Yang, D, Zhang, W, Amin, S, Wu, CJ, Wu, CC, Akbani, R, Aldape, K, Baggerly, KA, Broom, B, Casasent, TD, Cleland, J, Dodda, D, Edgerton, M, Han, L, Herbrich, SM, Ju, Z, Kim, H, Lerner, S, Li, J, Liang, H, Liu, W, Lorenzi, PL, Lu, Y, Melott, J, Nguyen, L, Su, X, Verhaak, R, Wang, W, Wong, A, Yang, Y, Yao, J, Yao, R, Yoshihara, K, Yuan, Y, Yung, AK, Zhang, N, Zheng, S, Ryan, M, Kane, DW, Aksoy, BA, Ciriello, G, Dresdner, G, Gao, J, Gross, B, Jacobsen, A, Kahles, A, Ladanyi, M, Lee, W, Lehmann, KV, Miller, ML, Ramirez, R, Rätsch, G, Reva, B, Schultz, N, Senbabaoglu, Y, Shen, R, Sinha, R, Sumer, SO, Sun, Y, Taylor, BS, Weinhold, N, Fei, S, Spellman, P, Benz, C, Carlin, D, Cline, M, Craft, B, Goldman, M, Haussler, D, Ma, S, Ng, S, Paull, E, Radenbaugh, A, Salama, S, Sokolov, A, Swatloski, T, Uzunangelov, V, Waltman, P, Yau, C, Zhu, J, Hamilton, SR, Abbott, S, Abbott, R, Dees, ND, Delehaunty, K, Ding, L, Dooling, DJ, Eldred, JM, Fronick, CC, Fulton, R, Fulton, LL, Kalicki-Veizer, J, Kanchi, KL, Kandoth, C, Koboldt, DC, Larson, DE, Ley, TJ, Lin, L, Lu, C, Magrini, VJ, Mardis, ER, McLellan, MD, McMichael, JF, Miller, CA, O'Laughlin, M, Pohl, C, Schmidt, H, Smith, SM, Walker, J, Wallis, JW, Wendl, MC, Wilson, RK, Wylie, T, Zhang, Q, Burton, R, Jensen, MA, Kahn, A, Pihl, T, Pot, D, Wan, Y, Levine, DA, Black, AD, Bowen, J, Frick, J, Gastier-Foster, JM, Harper, HA, Helsel, C, Leraas, KM, Lichtenberg, TM, McAllister, C, Ramirez, NC, Sharpe, S, Wise, L, Zmuda, E, Chanock, SJ, Davidsen, T, Demchok, JA, Eley, G, Felau, I, Sheth, M, Sofia, H, Staudt, L, Tarnuzzer, R, Wang, Z, Yang, L, Zhang, J, Omberg, L, Margolin, A, Raphael, BJ, Vandin, F, Wu, HT, Leiserson, MDM, Benz, SC, Vaske, CJ, Noushmehr, H, Wolf, D, Veer, LVT, Anastassiou, D, Yang, THO, Lopez-Bigas, N, Gonzalez-Perez, A, Tamborero, D, Xia, Z, Li, W, Cho, DY, Przytycka, T, Hamilton, M, McGuire, S, Nelander, S, Johansson, P, Jörnsten, R & Kling, T 2013, 'The cancer genome atlas pan-cancer analysis project', Nature Genetics, vol. 45, no. 10, pp. 1113-1120. https://doi.org/10.1038/ng.2764
Weinstein JN, Collisson EA, Mills GB, Shaw KRM, Ozenberger BA, Ellrott K et al. The cancer genome atlas pan-cancer analysis project. Nature Genetics. 2013 Oct 1;45(10):1113-1120. https://doi.org/10.1038/ng.2764
Weinstein, John N. ; Collisson, Eric A. ; Mills, Gordon B. ; Shaw, Kenna R.Mills ; Ozenberger, Brad A. ; Ellrott, Kyle ; Sander, Chris ; Stuart, Joshua M. ; Chang, Kyle ; Creighton, Chad J. ; Davis, Caleb ; Donehower, Lawrence ; Drummond, Jennifer ; Wheeler, David ; Ally, Adrian ; Balasundaram, Miruna ; Birol, Inanc ; Butterfield, Yaron S.N. ; Chu, Andy ; Chuah, Eric ; Chun, Hye Jung E. ; Dhalla, Noreen ; Guin, Ranabir ; Hirst, Martin ; Hirst, Carrie ; Holt, Robert A. ; Jones, Steven J.M. ; Lee, Darlene ; Li, Haiyan I. ; Marra, Marco A. ; Mayo, Michael ; Moore, Richard A. ; Mungall, Andrew J. ; Robertson, A. Gordon ; Schein, Jacqueline E. ; Sipahimalani, Payal ; Tam, Angela ; Thiessen, Nina ; Varhol, Richard J. ; Beroukhim, Rameen ; Bhatt, Ami S. ; Brooks, Angela N. ; Cherniack, Andrew D. ; Freeman, Samuel S. ; Gabriel, Stacey B. ; Helman, Elena ; Jung, Joonil ; Meyerson, Matthew ; Ojesina, Akinyemi I. ; Pedamallu, Chandra Sekhar ; Saksena, Gordon ; Schumacher, Steven E. ; Tabak, Barbara ; Zack, Travis ; Lander, Eric S. ; Bristow, Christopher A. ; Hadjipanayis, Angela ; Haseley, Psalm ; Kucherlapati, Raju ; Lee, Semin ; Lee, Eunjung ; Luquette, Lovelace J. ; Mahadeshwar, Harshad S. ; Pantazi, Angeliki ; Parfenov, Michael ; Park, Peter J. ; Protopopov, Alexei ; Ren, Xiaojia ; Santoso, Netty ; Seidman, Jonathan ; Seth, Sahil ; Song, Xingzhi ; Tang, Jiabin ; Xi, Ruibin ; Xu, Andrew W. ; Yang, Lixing ; Zeng, Dong ; Auman, J. Todd ; Balu, Saianand ; Buda, Elizabeth ; Fan, Cheng ; Hoadley, Katherine A. ; Jones, Corbin D. ; Meng, Shaowu ; Mieczkowski, Piotr A. ; Parker, Joel S. ; Perou, Charles M. ; Roach, Jeffrey ; Shi, Yan ; Silva, Grace O. ; Tan, Donghui ; Veluvolu, Umadevi ; Waring, Scot ; Wilkerson, Matthew D. ; Wu, Junyuan ; Zhao, Wei ; Bodenheimer, Tom ; Hayes, D. Neil ; Hoyle, Alan P. ; Jeffreys, Stuart R. ; Mose, Lisle E. ; Simons, Janae V. ; Soloway, Mathew G. ; Baylin, Stephen B. ; Berman, Benjamin P. ; Bootwalla, Moiz S. ; Danilova, Ludmila ; Herman, James G. ; Hinoue, Toshinori ; Laird, Peter W. ; Rhie, Suhn K. ; Shen, Hui ; Triche, Timothy ; Weisenberger, Daniel J. ; Carter, Scott L. ; Cibulskis, Kristian ; Chin, Lynda ; Zhang, Jianhua ; Sougnez, Carrie ; Wang, Min ; Getz, Gad ; Dinh, Huyen ; Doddapaneni, Harsha Vardhan ; Gibbs, Richard ; Gunaratne, Preethi ; Han, Yi ; Kalra, Divya ; Kovar, Christie ; Lewis, Lora ; Morgan, Margaret ; Morton, Donna ; Muzny, Donna ; Reid, Jeffrey ; Xi, Liu ; Cho, Juok ; Dicara, Daniel ; Frazer, Scott ; Gehlenborg, Nils ; Heiman, David I. ; Kim, Jaegil ; Lawrence, Michael S. ; Lin, Pei ; Liu, Yingchun ; Noble, Michael S. ; Stojanov, Petar ; Voet, Doug ; Zhang, Hailei ; Zou, Lihua ; Stewart, Chip ; Bernard, Brady ; Bressler, Ryan ; Eakin, Andrea ; Iype, Lisa ; Knijnenburg, Theo ; Kramer, Roger ; Kreisberg, Richard ; Leinonen, Kalle ; Lin, Jake ; Liu, Yuexin ; Miller, Michael ; Reynolds, Sheila M. ; Rovira, Hector ; Shmulevich, Ilya ; Thorsson, Vesteinn ; Yang, Da ; Zhang, Wei ; Amin, Samirkumar ; Wu, Chang Jiun ; Wu, Chia Chin ; Akbani, Rehan ; Aldape, Kenneth ; Baggerly, Keith A. ; Broom, Bradley ; Casasent, Tod D. ; Cleland, James ; Dodda, Deepti ; Edgerton, Mary ; Han, Leng ; Herbrich, Shelley M. ; Ju, Zhenlin ; Kim, Hoon ; Lerner, Seth ; Li, Jun ; Liang, Han ; Liu, Wenbin ; Lorenzi, Philip L. ; Lu, Yiling ; Melott, James ; Nguyen, Lam ; Su, Xiaoping ; Verhaak, Roeland ; Wang, Wenyi ; Wong, Andrew ; Yang, Yang ; Yao, Jun ; Yao, Rong ; Yoshihara, Kosuke ; Yuan, Yuan ; Yung, Alfred K. ; Zhang, Nianxiang ; Zheng, Siyuan ; Ryan, Michael ; Kane, David W. ; Aksoy, B. Arman ; Ciriello, Giovanni ; Dresdner, Gideon ; Gao, Jianjiong ; Gross, Benjamin ; Jacobsen, Anders ; Kahles, Andre ; Ladanyi, Marc ; Lee, William ; Lehmann, Kjong Van ; Miller, Martin L. ; Ramirez, Ricardo ; Rätsch, Gunnar ; Reva, Boris ; Schultz, Nikolaus ; Senbabaoglu, Yasin ; Shen, Ronglai ; Sinha, Rileen ; Sumer, S. Onur ; Sun, Yichao ; Taylor, Barry S. ; Weinhold, Nils ; Fei, Suzanne ; Spellman, Paul ; Benz, Christopher ; Carlin, Daniel ; Cline, Melisssa ; Craft, Brian ; Goldman, Mary ; Haussler, David ; Ma, Singer ; Ng, Sam ; Paull, Evan ; Radenbaugh, Amie ; Salama, Sofie ; Sokolov, Artem ; Swatloski, Teresa ; Uzunangelov, Vladislav ; Waltman, Peter ; Yau, Christina ; Zhu, Jing ; Hamilton, Stanley R. ; Abbott, Scott ; Abbott, Rachel ; Dees, Nathan D. ; Delehaunty, Kim ; Ding, Li ; Dooling, David J. ; Eldred, Jim M. ; Fronick, Catrina C. ; Fulton, Robert ; Fulton, Lucinda L. ; Kalicki-Veizer, Joelle ; Kanchi, Krishna Latha ; Kandoth, Cyriac ; Koboldt, Daniel C. ; Larson, David E. ; Ley, Timothy J. ; Lin, Ling ; Lu, Charles ; Magrini, Vincent J. ; Mardis, Elaine R. ; McLellan, Michael D. ; McMichael, Joshua F. ; Miller, Christopher A. ; O'Laughlin, Michelle ; Pohl, Craig ; Schmidt, Heather ; Smith, Scott M. ; Walker, Jason ; Wallis, John W. ; Wendl, Michael C. ; Wilson, Richard K. ; Wylie, Todd ; Zhang, Qunyuan ; Burton, Robert ; Jensen, Mark A. ; Kahn, Ari ; Pihl, Todd ; Pot, David ; Wan, Yunhu ; Levine, Douglas A. ; Black, Aaron D. ; Bowen, Jay ; Frick, Jessica ; Gastier-Foster, Julie M. ; Harper, Hollie A. ; Helsel, Carmen ; Leraas, Kristen M. ; Lichtenberg, Tara M. ; McAllister, Cynthia ; Ramirez, Nilsa C. ; Sharpe, Samantha ; Wise, Lisa ; Zmuda, Erik ; Chanock, Stephen J. ; Davidsen, Tanja ; Demchok, John A. ; Eley, Greg ; Felau, Ina ; Sheth, Margi ; Sofia, Heidi ; Staudt, Louis ; Tarnuzzer, Roy ; Wang, Zhining ; Yang, Liming ; Zhang, Jiashan ; Omberg, Larsson ; Margolin, Adam ; Raphael, Benjamin J. ; Vandin, Fabio ; Wu, Hsin Ta ; Leiserson, Mark D.M. ; Benz, Stephen C. ; Vaske, Charles J. ; Noushmehr, Houtan ; Wolf, Denise ; Veer, Laura Van T. ; Anastassiou, Dimitris ; Yang, Tai Hsien Ou ; Lopez-Bigas, Nuria ; Gonzalez-Perez, Abel ; Tamborero, David ; Xia, Zheng ; Li, Wei ; Cho, Dong Yeon ; Przytycka, Teresa ; Hamilton, Mark ; McGuire, Sean ; Nelander, Sven ; Johansson, Patrik ; Jörnsten, Rebecka ; Kling, Teresia. / The cancer genome atlas pan-cancer analysis project. In: Nature Genetics. 2013 ; Vol. 45, No. 10. pp. 1113-1120.
@article{09a3f4253c2747f7be937d726e549e1a,
title = "The cancer genome atlas pan-cancer analysis project",
abstract = "The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile.",
author = "Weinstein, {John N.} and Collisson, {Eric A.} and Mills, {Gordon B.} and Shaw, {Kenna R.Mills} and Ozenberger, {Brad A.} and Kyle Ellrott and Chris Sander and Stuart, {Joshua M.} and Kyle Chang and Creighton, {Chad J.} and Caleb Davis and Lawrence Donehower and Jennifer Drummond and David Wheeler and Adrian Ally and Miruna Balasundaram and Inanc Birol and Butterfield, {Yaron S.N.} and Andy Chu and Eric Chuah and Chun, {Hye Jung E.} and Noreen Dhalla and Ranabir Guin and Martin Hirst and Carrie Hirst and Holt, {Robert A.} and Jones, {Steven J.M.} and Darlene Lee and Li, {Haiyan I.} and Marra, {Marco A.} and Michael Mayo and Moore, {Richard A.} and Mungall, {Andrew J.} and Robertson, {A. Gordon} and Schein, {Jacqueline E.} and Payal Sipahimalani and Angela Tam and Nina Thiessen and Varhol, {Richard J.} and Rameen Beroukhim and Bhatt, {Ami S.} and Brooks, {Angela N.} and Cherniack, {Andrew D.} and Freeman, {Samuel S.} and Gabriel, {Stacey B.} and Elena Helman and Joonil Jung and Matthew Meyerson and Ojesina, {Akinyemi I.} and Pedamallu, {Chandra Sekhar} and Gordon Saksena and Schumacher, {Steven E.} and Barbara Tabak and Travis Zack and Lander, {Eric S.} and Bristow, {Christopher A.} and Angela Hadjipanayis and Psalm Haseley and Raju Kucherlapati and Semin Lee and Eunjung Lee and Luquette, {Lovelace J.} and Mahadeshwar, {Harshad S.} and Angeliki Pantazi and Michael Parfenov and Park, {Peter J.} and Alexei Protopopov and Xiaojia Ren and Netty Santoso and Jonathan Seidman and Sahil Seth and Xingzhi Song and Jiabin Tang and Ruibin Xi and Xu, {Andrew W.} and Lixing Yang and Dong Zeng and Auman, {J. Todd} and Saianand Balu and Elizabeth Buda and Cheng Fan and Hoadley, {Katherine A.} and Jones, {Corbin D.} and Shaowu Meng and Mieczkowski, {Piotr A.} and Parker, {Joel S.} and Perou, {Charles M.} and Jeffrey Roach and Yan Shi and Silva, {Grace O.} and Donghui Tan and Umadevi Veluvolu and Scot Waring and Wilkerson, {Matthew D.} and Junyuan Wu and Wei Zhao and Tom Bodenheimer and Hayes, {D. Neil} and Hoyle, {Alan P.} and Jeffreys, {Stuart R.} and Mose, {Lisle E.} and Simons, {Janae V.} and Soloway, {Mathew G.} and Baylin, {Stephen B.} and Berman, {Benjamin P.} and Bootwalla, {Moiz S.} and Ludmila Danilova and Herman, {James G.} and Toshinori Hinoue and Laird, {Peter W.} and Rhie, {Suhn K.} and Hui Shen and Timothy Triche and Weisenberger, {Daniel J.} and Carter, {Scott L.} and Kristian Cibulskis and Lynda Chin and Jianhua Zhang and Carrie Sougnez and Min Wang and Gad Getz and Huyen Dinh and Doddapaneni, {Harsha Vardhan} and Richard Gibbs and Preethi Gunaratne and Yi Han and Divya Kalra and Christie Kovar and Lora Lewis and Margaret Morgan and Donna Morton and Donna Muzny and Jeffrey Reid and Liu Xi and Juok Cho and Daniel Dicara and Scott Frazer and Nils Gehlenborg and Heiman, {David I.} and Jaegil Kim and Lawrence, {Michael S.} and Pei Lin and Yingchun Liu and Noble, {Michael S.} and Petar Stojanov and Doug Voet and Hailei Zhang and Lihua Zou and Chip Stewart and Brady Bernard and Ryan Bressler and Andrea Eakin and Lisa Iype and Theo Knijnenburg and Roger Kramer and Richard Kreisberg and Kalle Leinonen and Jake Lin and Yuexin Liu and Michael Miller and Reynolds, {Sheila M.} and Hector Rovira and Ilya Shmulevich and Vesteinn Thorsson and Da Yang and Wei Zhang and Samirkumar Amin and Wu, {Chang Jiun} and Wu, {Chia Chin} and Rehan Akbani and Kenneth Aldape and Baggerly, {Keith A.} and Bradley Broom and Casasent, {Tod D.} and James Cleland and Deepti Dodda and Mary Edgerton and Leng Han and Herbrich, {Shelley M.} and Zhenlin Ju and Hoon Kim and Seth Lerner and Jun Li and Han Liang and Wenbin Liu and Lorenzi, {Philip L.} and Yiling Lu and James Melott and Lam Nguyen and Xiaoping Su and Roeland Verhaak and Wenyi Wang and Andrew Wong and Yang Yang and Jun Yao and Rong Yao and Kosuke Yoshihara and Yuan Yuan and Yung, {Alfred K.} and Nianxiang Zhang and Siyuan Zheng and Michael Ryan and Kane, {David W.} and Aksoy, {B. Arman} and Giovanni Ciriello and Gideon Dresdner and Jianjiong Gao and Benjamin Gross and Anders Jacobsen and Andre Kahles and Marc Ladanyi and William Lee and Lehmann, {Kjong Van} and Miller, {Martin L.} and Ricardo Ramirez and Gunnar R{\"a}tsch and Boris Reva and Nikolaus Schultz and Yasin Senbabaoglu and Ronglai Shen and Rileen Sinha and Sumer, {S. Onur} and Yichao Sun and Taylor, {Barry S.} and Nils Weinhold and Suzanne Fei and Paul Spellman and Christopher Benz and Daniel Carlin and Melisssa Cline and Brian Craft and Mary Goldman and David Haussler and Singer Ma and Sam Ng and Evan Paull and Amie Radenbaugh and Sofie Salama and Artem Sokolov and Teresa Swatloski and Vladislav Uzunangelov and Peter Waltman and Christina Yau and Jing Zhu and Hamilton, {Stanley R.} and Scott Abbott and Rachel Abbott and Dees, {Nathan D.} and Kim Delehaunty and Li Ding and Dooling, {David J.} and Eldred, {Jim M.} and Fronick, {Catrina C.} and Robert Fulton and Fulton, {Lucinda L.} and Joelle Kalicki-Veizer and Kanchi, {Krishna Latha} and Cyriac Kandoth and Koboldt, {Daniel C.} and Larson, {David E.} and Ley, {Timothy J.} and Ling Lin and Charles Lu and Magrini, {Vincent J.} and Mardis, {Elaine R.} and McLellan, {Michael D.} and McMichael, {Joshua F.} and Miller, {Christopher A.} and Michelle O'Laughlin and Craig Pohl and Heather Schmidt and Smith, {Scott M.} and Jason Walker and Wallis, {John W.} and Wendl, {Michael C.} and Wilson, {Richard K.} and Todd Wylie and Qunyuan Zhang and Robert Burton and Jensen, {Mark A.} and Ari Kahn and Todd Pihl and David Pot and Yunhu Wan and Levine, {Douglas A.} and Black, {Aaron D.} and Jay Bowen and Jessica Frick and Gastier-Foster, {Julie M.} and Harper, {Hollie A.} and Carmen Helsel and Leraas, {Kristen M.} and Lichtenberg, {Tara M.} and Cynthia McAllister and Ramirez, {Nilsa C.} and Samantha Sharpe and Lisa Wise and Erik Zmuda and Chanock, {Stephen J.} and Tanja Davidsen and Demchok, {John A.} and Greg Eley and Ina Felau and Margi Sheth and Heidi Sofia and Louis Staudt and Roy Tarnuzzer and Zhining Wang and Liming Yang and Jiashan Zhang and Larsson Omberg and Adam Margolin and Raphael, {Benjamin J.} and Fabio Vandin and Wu, {Hsin Ta} and Leiserson, {Mark D.M.} and Benz, {Stephen C.} and Vaske, {Charles J.} and Houtan Noushmehr and Denise Wolf and Veer, {Laura Van T.} and Dimitris Anastassiou and Yang, {Tai Hsien Ou} and Nuria Lopez-Bigas and Abel Gonzalez-Perez and David Tamborero and Zheng Xia and Wei Li and Cho, {Dong Yeon} and Teresa Przytycka and Mark Hamilton and Sean McGuire and Sven Nelander and Patrik Johansson and Rebecka J{\"o}rnsten and Teresia Kling",
year = "2013",
month = "10",
day = "1",
doi = "10.1038/ng.2764",
language = "English (US)",
volume = "45",
pages = "1113--1120",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Publishing Group",
number = "10",

}

TY - JOUR

T1 - The cancer genome atlas pan-cancer analysis project

AU - Weinstein, John N.

AU - Collisson, Eric A.

AU - Mills, Gordon B.

AU - Shaw, Kenna R.Mills

AU - Ozenberger, Brad A.

AU - Ellrott, Kyle

AU - Sander, Chris

AU - Stuart, Joshua M.

AU - Chang, Kyle

AU - Creighton, Chad J.

AU - Davis, Caleb

AU - Donehower, Lawrence

AU - Drummond, Jennifer

AU - Wheeler, David

AU - Ally, Adrian

AU - Balasundaram, Miruna

AU - Birol, Inanc

AU - Butterfield, Yaron S.N.

AU - Chu, Andy

AU - Chuah, Eric

AU - Chun, Hye Jung E.

AU - Dhalla, Noreen

AU - Guin, Ranabir

AU - Hirst, Martin

AU - Hirst, Carrie

AU - Holt, Robert A.

AU - Jones, Steven J.M.

AU - Lee, Darlene

AU - Li, Haiyan I.

AU - Marra, Marco A.

AU - Mayo, Michael

AU - Moore, Richard A.

AU - Mungall, Andrew J.

AU - Robertson, A. Gordon

AU - Schein, Jacqueline E.

AU - Sipahimalani, Payal

AU - Tam, Angela

AU - Thiessen, Nina

AU - Varhol, Richard J.

AU - Beroukhim, Rameen

AU - Bhatt, Ami S.

AU - Brooks, Angela N.

AU - Cherniack, Andrew D.

AU - Freeman, Samuel S.

AU - Gabriel, Stacey B.

AU - Helman, Elena

AU - Jung, Joonil

AU - Meyerson, Matthew

AU - Ojesina, Akinyemi I.

AU - Pedamallu, Chandra Sekhar

AU - Saksena, Gordon

AU - Schumacher, Steven E.

AU - Tabak, Barbara

AU - Zack, Travis

AU - Lander, Eric S.

AU - Bristow, Christopher A.

AU - Hadjipanayis, Angela

AU - Haseley, Psalm

AU - Kucherlapati, Raju

AU - Lee, Semin

AU - Lee, Eunjung

AU - Luquette, Lovelace J.

AU - Mahadeshwar, Harshad S.

AU - Pantazi, Angeliki

AU - Parfenov, Michael

AU - Park, Peter J.

AU - Protopopov, Alexei

AU - Ren, Xiaojia

AU - Santoso, Netty

AU - Seidman, Jonathan

AU - Seth, Sahil

AU - Song, Xingzhi

AU - Tang, Jiabin

AU - Xi, Ruibin

AU - Xu, Andrew W.

AU - Yang, Lixing

AU - Zeng, Dong

AU - Auman, J. Todd

AU - Balu, Saianand

AU - Buda, Elizabeth

AU - Fan, Cheng

AU - Hoadley, Katherine A.

AU - Jones, Corbin D.

AU - Meng, Shaowu

AU - Mieczkowski, Piotr A.

AU - Parker, Joel S.

AU - Perou, Charles M.

AU - Roach, Jeffrey

AU - Shi, Yan

AU - Silva, Grace O.

AU - Tan, Donghui

AU - Veluvolu, Umadevi

AU - Waring, Scot

AU - Wilkerson, Matthew D.

AU - Wu, Junyuan

AU - Zhao, Wei

AU - Bodenheimer, Tom

AU - Hayes, D. Neil

AU - Hoyle, Alan P.

AU - Jeffreys, Stuart R.

AU - Mose, Lisle E.

AU - Simons, Janae V.

AU - Soloway, Mathew G.

AU - Baylin, Stephen B.

AU - Berman, Benjamin P.

AU - Bootwalla, Moiz S.

AU - Danilova, Ludmila

AU - Herman, James G.

AU - Hinoue, Toshinori

AU - Laird, Peter W.

AU - Rhie, Suhn K.

AU - Shen, Hui

AU - Triche, Timothy

AU - Weisenberger, Daniel J.

AU - Carter, Scott L.

AU - Cibulskis, Kristian

AU - Chin, Lynda

AU - Zhang, Jianhua

AU - Sougnez, Carrie

AU - Wang, Min

AU - Getz, Gad

AU - Dinh, Huyen

AU - Doddapaneni, Harsha Vardhan

AU - Gibbs, Richard

AU - Gunaratne, Preethi

AU - Han, Yi

AU - Kalra, Divya

AU - Kovar, Christie

AU - Lewis, Lora

AU - Morgan, Margaret

AU - Morton, Donna

AU - Muzny, Donna

AU - Reid, Jeffrey

AU - Xi, Liu

AU - Cho, Juok

AU - Dicara, Daniel

AU - Frazer, Scott

AU - Gehlenborg, Nils

AU - Heiman, David I.

AU - Kim, Jaegil

AU - Lawrence, Michael S.

AU - Lin, Pei

AU - Liu, Yingchun

AU - Noble, Michael S.

AU - Stojanov, Petar

AU - Voet, Doug

AU - Zhang, Hailei

AU - Zou, Lihua

AU - Stewart, Chip

AU - Bernard, Brady

AU - Bressler, Ryan

AU - Eakin, Andrea

AU - Iype, Lisa

AU - Knijnenburg, Theo

AU - Kramer, Roger

AU - Kreisberg, Richard

AU - Leinonen, Kalle

AU - Lin, Jake

AU - Liu, Yuexin

AU - Miller, Michael

AU - Reynolds, Sheila M.

AU - Rovira, Hector

AU - Shmulevich, Ilya

AU - Thorsson, Vesteinn

AU - Yang, Da

AU - Zhang, Wei

AU - Amin, Samirkumar

AU - Wu, Chang Jiun

AU - Wu, Chia Chin

AU - Akbani, Rehan

AU - Aldape, Kenneth

AU - Baggerly, Keith A.

AU - Broom, Bradley

AU - Casasent, Tod D.

AU - Cleland, James

AU - Dodda, Deepti

AU - Edgerton, Mary

AU - Han, Leng

AU - Herbrich, Shelley M.

AU - Ju, Zhenlin

AU - Kim, Hoon

AU - Lerner, Seth

AU - Li, Jun

AU - Liang, Han

AU - Liu, Wenbin

AU - Lorenzi, Philip L.

AU - Lu, Yiling

AU - Melott, James

AU - Nguyen, Lam

AU - Su, Xiaoping

AU - Verhaak, Roeland

AU - Wang, Wenyi

AU - Wong, Andrew

AU - Yang, Yang

AU - Yao, Jun

AU - Yao, Rong

AU - Yoshihara, Kosuke

AU - Yuan, Yuan

AU - Yung, Alfred K.

AU - Zhang, Nianxiang

AU - Zheng, Siyuan

AU - Ryan, Michael

AU - Kane, David W.

AU - Aksoy, B. Arman

AU - Ciriello, Giovanni

AU - Dresdner, Gideon

AU - Gao, Jianjiong

AU - Gross, Benjamin

AU - Jacobsen, Anders

AU - Kahles, Andre

AU - Ladanyi, Marc

AU - Lee, William

AU - Lehmann, Kjong Van

AU - Miller, Martin L.

AU - Ramirez, Ricardo

AU - Rätsch, Gunnar

AU - Reva, Boris

AU - Schultz, Nikolaus

AU - Senbabaoglu, Yasin

AU - Shen, Ronglai

AU - Sinha, Rileen

AU - Sumer, S. Onur

AU - Sun, Yichao

AU - Taylor, Barry S.

AU - Weinhold, Nils

AU - Fei, Suzanne

AU - Spellman, Paul

AU - Benz, Christopher

AU - Carlin, Daniel

AU - Cline, Melisssa

AU - Craft, Brian

AU - Goldman, Mary

AU - Haussler, David

AU - Ma, Singer

AU - Ng, Sam

AU - Paull, Evan

AU - Radenbaugh, Amie

AU - Salama, Sofie

AU - Sokolov, Artem

AU - Swatloski, Teresa

AU - Uzunangelov, Vladislav

AU - Waltman, Peter

AU - Yau, Christina

AU - Zhu, Jing

AU - Hamilton, Stanley R.

AU - Abbott, Scott

AU - Abbott, Rachel

AU - Dees, Nathan D.

AU - Delehaunty, Kim

AU - Ding, Li

AU - Dooling, David J.

AU - Eldred, Jim M.

AU - Fronick, Catrina C.

AU - Fulton, Robert

AU - Fulton, Lucinda L.

AU - Kalicki-Veizer, Joelle

AU - Kanchi, Krishna Latha

AU - Kandoth, Cyriac

AU - Koboldt, Daniel C.

AU - Larson, David E.

AU - Ley, Timothy J.

AU - Lin, Ling

AU - Lu, Charles

AU - Magrini, Vincent J.

AU - Mardis, Elaine R.

AU - McLellan, Michael D.

AU - McMichael, Joshua F.

AU - Miller, Christopher A.

AU - O'Laughlin, Michelle

AU - Pohl, Craig

AU - Schmidt, Heather

AU - Smith, Scott M.

AU - Walker, Jason

AU - Wallis, John W.

AU - Wendl, Michael C.

AU - Wilson, Richard K.

AU - Wylie, Todd

AU - Zhang, Qunyuan

AU - Burton, Robert

AU - Jensen, Mark A.

AU - Kahn, Ari

AU - Pihl, Todd

AU - Pot, David

AU - Wan, Yunhu

AU - Levine, Douglas A.

AU - Black, Aaron D.

AU - Bowen, Jay

AU - Frick, Jessica

AU - Gastier-Foster, Julie M.

AU - Harper, Hollie A.

AU - Helsel, Carmen

AU - Leraas, Kristen M.

AU - Lichtenberg, Tara M.

AU - McAllister, Cynthia

AU - Ramirez, Nilsa C.

AU - Sharpe, Samantha

AU - Wise, Lisa

AU - Zmuda, Erik

AU - Chanock, Stephen J.

AU - Davidsen, Tanja

AU - Demchok, John A.

AU - Eley, Greg

AU - Felau, Ina

AU - Sheth, Margi

AU - Sofia, Heidi

AU - Staudt, Louis

AU - Tarnuzzer, Roy

AU - Wang, Zhining

AU - Yang, Liming

AU - Zhang, Jiashan

AU - Omberg, Larsson

AU - Margolin, Adam

AU - Raphael, Benjamin J.

AU - Vandin, Fabio

AU - Wu, Hsin Ta

AU - Leiserson, Mark D.M.

AU - Benz, Stephen C.

AU - Vaske, Charles J.

AU - Noushmehr, Houtan

AU - Wolf, Denise

AU - Veer, Laura Van T.

AU - Anastassiou, Dimitris

AU - Yang, Tai Hsien Ou

AU - Lopez-Bigas, Nuria

AU - Gonzalez-Perez, Abel

AU - Tamborero, David

AU - Xia, Zheng

AU - Li, Wei

AU - Cho, Dong Yeon

AU - Przytycka, Teresa

AU - Hamilton, Mark

AU - McGuire, Sean

AU - Nelander, Sven

AU - Johansson, Patrik

AU - Jörnsten, Rebecka

AU - Kling, Teresia

PY - 2013/10/1

Y1 - 2013/10/1

N2 - The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile.

AB - The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile.

UR - http://www.scopus.com/inward/record.url?scp=84884994218&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84884994218&partnerID=8YFLogxK

U2 - 10.1038/ng.2764

DO - 10.1038/ng.2764

M3 - Review article

VL - 45

SP - 1113

EP - 1120

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 10

ER -