The biocompatibility of compressed collagen foam plugs

Jeffrey D. Robinson, Joseph W. Yedlicka, Mark C. Bildsoe, Zeev Vlodaver, David W. Hunter, Wilfrido Castañeda-Zúñiga, Kurt Amplatz

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The tissue reaction to reexpanded, purified bovine collagen sponge placed percutaneously into the lung, pleural space, liver, kidney, and muscle was studied in dogs and rabbits. In addition, the biocompatibility and radiopacity of tantalumtreated collagen foam plugs was examined. No adverse effects were found. We believe that collagen plugs may be of use in occluding needle tracts from biopsy sites to prevent complications such as bleeding or pneumothoraces.

Original languageEnglish (US)
Pages (from-to)36-39
Number of pages4
JournalCardiovascular and Interventional Radiology
Issue number1
StatePublished - Feb 1 1990


  • Biocompatibility
  • Biopsy
  • Gelfoam plugs
  • Pneumothorax
  • Tantalum

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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