The BEIR VII estimates of low-dose radiation health risks are based on faulty assumptions and data analyses: A call for reassessment

Jeffry A. Siegel, Bennett S. Greenspan, Alan H. Maurer, Andrew T. Taylor, William T Phillips, Douglas Van Nostrand, Bill Sacks, Edward B. Silberstein

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

The 2006 National Academy of Sciences Biologic Effects of Ionizing Radiation (BEIR) VII report is a well-recognized and frequently cited source on the legitimacy of the linear no-threshold (LNT) model-a model entailing a linear and causal relationship between ionizing radiation and human cancer risk. Linearity means that all radiation causes cancer and explicitly excludes a threshold below which radiogenic cancer risk disappears. However, the BEIR VII committee has erred in the interpretation of its selected literature; specifically, the in vitro data quoted fail to support LNT. Moreover, in vitro data cannot be considered as definitive proof of cancer development in intact organisms. This review is presented to stimulate a critical reevaluation by a BEIR VIII committee to reassess the validity, and use, of LNT and its derived policies.

Original languageEnglish (US)
Pages (from-to)1017-1019
Number of pages3
JournalJournal of Nuclear Medicine
Volume59
Issue number7
DOIs
StatePublished - Jul 1 2018

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Keywords

  • BEIR VII
  • Linear no-threshold
  • Radiological imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Siegel, J. A., Greenspan, B. S., Maurer, A. H., Taylor, A. T., Phillips, W. T., Van Nostrand, D., Sacks, B., & Silberstein, E. B. (2018). The BEIR VII estimates of low-dose radiation health risks are based on faulty assumptions and data analyses: A call for reassessment. Journal of Nuclear Medicine, 59(7), 1017-1019. https://doi.org/10.2967/jnumed.117.206219