TY - JOUR
T1 - The Automated Complete Blood Cell Count
T2 - Use of the Red Blood Cell Volume Distribution Width and Mean Platelet Volume in Evaluating Anemia and Thrombocytopenia
AU - Karnad, Anand
AU - Poskitt, Thomas R.
PY - 1985/7
Y1 - 1985/7
N2 - The availability of automated blood cell analyzers that provide an index of red blood cell volume distribution width (RDW) and a mean platelet volume (MPV) has led to new approaches to patients with anemia and thrombocytopenia. The RDW, which measures heterogeneity of the red blood cell population, complements the mean corpuscular volume in the differential diagnosis of anemia based on peripheral blood analysis. The MPV varies inversely but nonlinearly with the platelet count in normal individuals and is of value in assessing platelet production in the thrombocytopenic patient. The clinical applications of the RDW and MPV, which are currently reported on most routine blood cell counts, are discussed.
AB - The availability of automated blood cell analyzers that provide an index of red blood cell volume distribution width (RDW) and a mean platelet volume (MPV) has led to new approaches to patients with anemia and thrombocytopenia. The RDW, which measures heterogeneity of the red blood cell population, complements the mean corpuscular volume in the differential diagnosis of anemia based on peripheral blood analysis. The MPV varies inversely but nonlinearly with the platelet count in normal individuals and is of value in assessing platelet production in the thrombocytopenic patient. The clinical applications of the RDW and MPV, which are currently reported on most routine blood cell counts, are discussed.
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U2 - 10.1001/archinte.1985.00360070150025
DO - 10.1001/archinte.1985.00360070150025
M3 - Article
C2 - 4015277
AN - SCOPUS:0021966793
SN - 0003-9926
VL - 145
SP - 1270
EP - 1272
JO - Archives of Internal Medicine
JF - Archives of Internal Medicine
IS - 7
ER -