The association of openness personality trait with stress-related salivary biomarkers in burning mouth syndrome

Fabrício T.A. De Souza; Arthur Kummer; Maiza L.V. Silva; Tânia M.P. Amaral; Evandro N. Abdo; Mauro H.N.G. Abreu; Tarcília A. Silva; Antônio L. Teixeira

doi:10.1159/000367714

The association of openness personality trait with stress-related salivary biomarkers in burning mouth syndrome

Fabrício T.A. De Souza, Arthur Kummer, Maiza L.V. Silva, Tânia M.P. Amaral, Evandro N. Abdo, Mauro H.N.G. Abreu, Tarcília A. Silva, Antônio L. Teixeira

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

Background: Burning mouth syndrome (BMS) is a chronic disorder defined as a burning sensation in the oral mucosa without evidence of pathological findings. Its pathophysiology is largely unknown, but psychiatric disorders and personality traits have been implicated. Objective: This study investigated whether there is any association between salivary biomarkers and personality traits in BMS patients. Methods: It was a cross-sectional, controlled study that evaluated 30 individuals with BMS and 32 controls. All subjects were assessed with a structured psychiatric interview (Mini International Neuropsychiatric Interview) and the Big Five inventory. Salivary levels of brain-derived neurotrophic factor (BDNF), neural growth factor, tumor necrosis factor-α, interleukin (IL)-6, IL-10 and cortisol were determined. Results: We found that BMS patients exhibited more traits of neuroticism and lower openness than controls. Openness showed a moderate and negative correlation with cortisol, BDNF and IL-6. Conclusion: Personality traits are associated with salivary biomarkers in BMS.

Original language	English (US)
Pages (from-to)	250-255
Number of pages	6
Journal	NeuroImmunoModulation
Volume	22
Issue number	4
DOIs	https://doi.org/10.1159/000367714
State	Published - Apr 24 2015
Externally published	Yes

Keywords

Burning mouth syndrome
Personality traits
Psychobiology
Psychopathology
Salivary biomarkers

ASJC Scopus subject areas

Immunology
Endocrinology
Neurology
Endocrine and Autonomic Systems

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10.1159/000367714

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title = "The association of openness personality trait with stress-related salivary biomarkers in burning mouth syndrome",

abstract = "Background: Burning mouth syndrome (BMS) is a chronic disorder defined as a burning sensation in the oral mucosa without evidence of pathological findings. Its pathophysiology is largely unknown, but psychiatric disorders and personality traits have been implicated. Objective: This study investigated whether there is any association between salivary biomarkers and personality traits in BMS patients. Methods: It was a cross-sectional, controlled study that evaluated 30 individuals with BMS and 32 controls. All subjects were assessed with a structured psychiatric interview (Mini International Neuropsychiatric Interview) and the Big Five inventory. Salivary levels of brain-derived neurotrophic factor (BDNF), neural growth factor, tumor necrosis factor-α, interleukin (IL)-6, IL-10 and cortisol were determined. Results: We found that BMS patients exhibited more traits of neuroticism and lower openness than controls. Openness showed a moderate and negative correlation with cortisol, BDNF and IL-6. Conclusion: Personality traits are associated with salivary biomarkers in BMS.",

keywords = "Burning mouth syndrome, Personality traits, Psychobiology, Psychopathology, Salivary biomarkers",

author = "{De Souza}, {Fabr{\'i}cio T.A.} and Arthur Kummer and Silva, {Maiza L.V.} and Amaral, {T{\^a}nia M.P.} and Abdo, {Evandro N.} and Abreu, {Mauro H.N.G.} and Silva, {Tarc{\'i}lia A.} and Teixeira, {Ant{\^o}nio L.}",

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year = "2015",

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doi = "10.1159/000367714",

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AU - De Souza, Fabrício T.A.

AU - Kummer, Arthur

AU - Silva, Maiza L.V.

AU - Amaral, Tânia M.P.

AU - Abdo, Evandro N.

AU - Abreu, Mauro H.N.G.

AU - Silva, Tarcília A.

AU - Teixeira, Antônio L.

PY - 2015/4/24

Y1 - 2015/4/24

N2 - Background: Burning mouth syndrome (BMS) is a chronic disorder defined as a burning sensation in the oral mucosa without evidence of pathological findings. Its pathophysiology is largely unknown, but psychiatric disorders and personality traits have been implicated. Objective: This study investigated whether there is any association between salivary biomarkers and personality traits in BMS patients. Methods: It was a cross-sectional, controlled study that evaluated 30 individuals with BMS and 32 controls. All subjects were assessed with a structured psychiatric interview (Mini International Neuropsychiatric Interview) and the Big Five inventory. Salivary levels of brain-derived neurotrophic factor (BDNF), neural growth factor, tumor necrosis factor-α, interleukin (IL)-6, IL-10 and cortisol were determined. Results: We found that BMS patients exhibited more traits of neuroticism and lower openness than controls. Openness showed a moderate and negative correlation with cortisol, BDNF and IL-6. Conclusion: Personality traits are associated with salivary biomarkers in BMS.

AB - Background: Burning mouth syndrome (BMS) is a chronic disorder defined as a burning sensation in the oral mucosa without evidence of pathological findings. Its pathophysiology is largely unknown, but psychiatric disorders and personality traits have been implicated. Objective: This study investigated whether there is any association between salivary biomarkers and personality traits in BMS patients. Methods: It was a cross-sectional, controlled study that evaluated 30 individuals with BMS and 32 controls. All subjects were assessed with a structured psychiatric interview (Mini International Neuropsychiatric Interview) and the Big Five inventory. Salivary levels of brain-derived neurotrophic factor (BDNF), neural growth factor, tumor necrosis factor-α, interleukin (IL)-6, IL-10 and cortisol were determined. Results: We found that BMS patients exhibited more traits of neuroticism and lower openness than controls. Openness showed a moderate and negative correlation with cortisol, BDNF and IL-6. Conclusion: Personality traits are associated with salivary biomarkers in BMS.

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The association of openness personality trait with stress-related salivary biomarkers in burning mouth syndrome

Abstract

Keywords

ASJC Scopus subject areas

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