The aspartate-257 of presenilin 1 is indispensable for mouse development and production of β-amyloid peptides through β-catenin-independent mechanisms

Neuroscience

• Presenilin 1 100%
• Proteolytic Processing 50%
• Peptide 33%
• Aspartic Acid 33%
• Amyloid 33%
• Catenin 33%
• Amyloid Precursor Protein 16%
• Phenotype 16%
• Alanine 16%
• Amino Acids 16%

Biochemistry, Genetics and Molecular Biology

• Notch 50%
• Peptide 33%
• Amyloid 33%
• Catenin 33%
• Amyloid Precursor Protein 16%
• Allele 16%
• Mutation 16%
• Phenotype 16%
• Transgenic Mouse 16%
• Protein Catabolism 16%
• Alanine 16%
• Development 16%
• Nerve Cell Culture 16%
• Mouse 16%

Immunology and Microbiology

• Catenin 33%
• Phenotype 16%
• Mutation 16%
• Protein Degradation 16%
• Transgenic Mouse 16%
• Allele 16%
• Nerve Cell Culture 16%
• Mouse 16%
• Development 16%