Abstract
Antimicrobial stewardship in the neonatal intensive care unit is a critically important tool to optimize clinical outcomes. The ideal duration of antimicrobial treatment is a key area that contains many knowledge gaps. This narrative review has three aims. One, to highlight the existing evidence for empiric and definitive antibiotic treatment durations for infants; two, to focus on clinical situations where further studies are needed; and three, to propose a rational, goal-based approach to clinical studies that provide for infant safety as shorter treatment durations are investigated.
| Original language | English (US) |
|---|---|
| Article number | 228 |
| Journal | Antibiotics |
| Volume | 15 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 2026 |
| Externally published | Yes |
Keywords
- antibiotic
- meningitis
- necrotizing enterocolitis
- neonate
- sepsis
- stewardship
ASJC Scopus subject areas
- Microbiology
- Biochemistry
- General Pharmacology, Toxicology and Pharmaceutics
- Microbiology (medical)
- Pharmacology (medical)
- Infectious Diseases
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