TGF-β antagonists: Same knot, but different hold

Andrew P. Hinck, Tao Huang

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations


In this issue of Structure, Nolan and colleagues present the structure of BMP antagonist, PRDC, which adopts a head-to-tail dimer with distinct structure and inhibitory mechanism compared to other dimeric antagonists of the TGF-β superfamily, such as noggin.

Original languageEnglish (US)
Pages (from-to)1269-1270
Number of pages2
Issue number8
StatePublished - Aug 6 2013

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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