Testicular Tumors

J. B. Lin, D. Troyer

Research output: Chapter in Book/Report/Conference proceedingChapter


This article will discuss various types of testicular and paratesticular tumors. We will begin with testicular germ cell tumors and a brief history of breakthrough in treatment of this disease, followed by utiLization of several serum markers as a tool in the initial workup and diagnosis of testicular cancer and subsequent posttherapy follow-up of the disease. Then, we will go over the pathogenesis of the testicular germ cell neoplasm. We will discuss intratubular germ cell neoplasia, seminoma (classic and spermatocytic), embryonal carcinoma, yolk sac tumors, teratoma, and trophoblastic tumors (choriocarcinoma) as well as demographic distribution (age), gross and microscopic appearance of each tumor, immunohistochemical stain profile, and prognosis. We will cover sex cord-stromal tumors, such as Leydig cell tumors, SertoLi cell tumors, granulosa cell tumors (adult and juvenile types), and other tumors of the testes, such as lymphoma, in a similar fashion. Finally, we will discuss paratesticular tumors arising from the epididymis, rete testis, and spermatic cord.

Original languageEnglish (US)
Title of host publicationPathobiology of Human Disease
Subtitle of host publicationA Dynamic Encyclopedia of Disease Mechanisms
PublisherElsevier Inc.
Number of pages16
ISBN (Electronic)9780123864567
ISBN (Print)9780123864574
StatePublished - Jan 1 2014


  • Embryonal carcinoma
  • Epididymal tumors
  • Granulosa cell tumors
  • Human testis germ cell tumors
  • Human testis non-germ cell/sex cord-stromal tumors
  • Human testis tumors
  • Leydig cell tumors
  • Mixed germ cell tumors
  • Mixed germ cell-sex cord-stromal tumors
  • Other paratesticular tumors
  • Other tumors
  • Paratesticular tumors
  • Rete testis tumors
  • Seminoma
  • SertoLi cell tumors
  • Serum markers of testicular cancer
  • Teratoma
  • Trophoblastic tumors
  • Yolk sac tumor

ASJC Scopus subject areas

  • Medicine(all)


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