Testicular Anatomy and Physiology

J. B. Lin; D. Troyer

doi:10.1016/B978-0-12-386456-7.05102-9

Testicular Anatomy and Physiology

J. B. Lin, D. Troyer

Department of Pathology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

In this article, we will discuss the testes and their appendages, starting from the germ cells in the allantois to the subsequent migration and development. We will discuss the most important cell types in the testis: germ cells, SertoLi cells, and Leydig cells. The interactions among these three cell types in addition to the hormones secreted by the pituitary gland are important for normal spermatogenesis. We will discuss the roles of epididymis, vas deferens, and seminal vesicle sperm maturation, transportation, and motiLity. As an endocrine organ, we will discuss the androgen pathway and the roles of androgen on benign and neoplastic prostatic tissue growth. Finally, we will discuss pharmaceutical agents used in treatment of benign prostatic hypertrophy and prostate cancer.

Original language	English (US)
Title of host publication	Pathobiology of Human Disease
Subtitle of host publication	A Dynamic Encyclopedia of Disease Mechanisms
Publisher	Elsevier Inc.
Pages	2464-2475
Number of pages	12
ISBN (Electronic)	9780123864567
ISBN (Print)	9780123864574
DOIs	https://doi.org/10.1016/B978-0-12-386456-7.05102-9
State	Published - Jan 1 2014

Keywords

5Alpha-reductase inhibitor (5ARI)
Androgen deprivation therapy (ADT)
Androgen pathway
DuctuLi efferentia
Epididymis
Germ cells
Human testis anatomy
Human testis development
Human testis vessels and nerves
Leydig cells
Physiology and physiopathology
Seminal vesicles
SertoLi cells
Spermatogenesis
Spermiogenesis
Testicular appendages
Vas deferens

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-386456-7.05102-9

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title = "Testicular Anatomy and Physiology",

abstract = "In this article, we will discuss the testes and their appendages, starting from the germ cells in the allantois to the subsequent migration and development. We will discuss the most important cell types in the testis: germ cells, SertoLi cells, and Leydig cells. The interactions among these three cell types in addition to the hormones secreted by the pituitary gland are important for normal spermatogenesis. We will discuss the roles of epididymis, vas deferens, and seminal vesicle sperm maturation, transportation, and motiLity. As an endocrine organ, we will discuss the androgen pathway and the roles of androgen on benign and neoplastic prostatic tissue growth. Finally, we will discuss pharmaceutical agents used in treatment of benign prostatic hypertrophy and prostate cancer.",

keywords = "5Alpha-reductase inhibitor (5ARI), Androgen deprivation therapy (ADT), Androgen pathway, DuctuLi efferentia, Epididymis, Germ cells, Human testis anatomy, Human testis development, Human testis vessels and nerves, Leydig cells, Physiology and physiopathology, Seminal vesicles, SertoLi cells, Spermatogenesis, Spermiogenesis, Testicular appendages, Vas deferens",

author = "Lin, {J. B.} and D. Troyer",

year = "2014",

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day = "1",

doi = "10.1016/B978-0-12-386456-7.05102-9",

language = "English (US)",

isbn = "9780123864574",

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AU - Lin, J. B.

AU - Troyer, D.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - In this article, we will discuss the testes and their appendages, starting from the germ cells in the allantois to the subsequent migration and development. We will discuss the most important cell types in the testis: germ cells, SertoLi cells, and Leydig cells. The interactions among these three cell types in addition to the hormones secreted by the pituitary gland are important for normal spermatogenesis. We will discuss the roles of epididymis, vas deferens, and seminal vesicle sperm maturation, transportation, and motiLity. As an endocrine organ, we will discuss the androgen pathway and the roles of androgen on benign and neoplastic prostatic tissue growth. Finally, we will discuss pharmaceutical agents used in treatment of benign prostatic hypertrophy and prostate cancer.

AB - In this article, we will discuss the testes and their appendages, starting from the germ cells in the allantois to the subsequent migration and development. We will discuss the most important cell types in the testis: germ cells, SertoLi cells, and Leydig cells. The interactions among these three cell types in addition to the hormones secreted by the pituitary gland are important for normal spermatogenesis. We will discuss the roles of epididymis, vas deferens, and seminal vesicle sperm maturation, transportation, and motiLity. As an endocrine organ, we will discuss the androgen pathway and the roles of androgen on benign and neoplastic prostatic tissue growth. Finally, we will discuss pharmaceutical agents used in treatment of benign prostatic hypertrophy and prostate cancer.

KW - 5Alpha-reductase inhibitor (5ARI)

KW - Androgen deprivation therapy (ADT)

KW - Androgen pathway

KW - DuctuLi efferentia

KW - Epididymis

KW - Germ cells

KW - Human testis anatomy

KW - Human testis development

KW - Human testis vessels and nerves

KW - Leydig cells

KW - Physiology and physiopathology

KW - Seminal vesicles

KW - SertoLi cells

KW - Spermatogenesis

KW - Spermiogenesis

KW - Testicular appendages

KW - Vas deferens

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DO - 10.1016/B978-0-12-386456-7.05102-9

M3 - Chapter

AN - SCOPUS:85043264876

SN - 9780123864574

SP - 2464

EP - 2475

BT - Pathobiology of Human Disease

PB - Elsevier Inc.

ER -

Testicular Anatomy and Physiology

Abstract

Keywords

ASJC Scopus subject areas

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