Testicular Anatomy and Physiology

J. B. Lin, D. Troyer

Research output: Chapter in Book/Report/Conference proceedingChapter


In this article, we will discuss the testes and their appendages, starting from the germ cells in the allantois to the subsequent migration and development. We will discuss the most important cell types in the testis: germ cells, SertoLi cells, and Leydig cells. The interactions among these three cell types in addition to the hormones secreted by the pituitary gland are important for normal spermatogenesis. We will discuss the roles of epididymis, vas deferens, and seminal vesicle sperm maturation, transportation, and motiLity. As an endocrine organ, we will discuss the androgen pathway and the roles of androgen on benign and neoplastic prostatic tissue growth. Finally, we will discuss pharmaceutical agents used in treatment of benign prostatic hypertrophy and prostate cancer.

Original languageEnglish (US)
Title of host publicationPathobiology of Human Disease
Subtitle of host publicationA Dynamic Encyclopedia of Disease Mechanisms
PublisherElsevier Inc.
Number of pages12
ISBN (Electronic)9780123864567
ISBN (Print)9780123864574
StatePublished - Jan 1 2014


  • 5Alpha-reductase inhibitor (5ARI)
  • Androgen deprivation therapy (ADT)
  • Androgen pathway
  • DuctuLi efferentia
  • Epididymis
  • Germ cells
  • Human testis anatomy
  • Human testis development
  • Human testis vessels and nerves
  • Leydig cells
  • Physiology and physiopathology
  • Seminal vesicles
  • SertoLi cells
  • Spermatogenesis
  • Spermiogenesis
  • Testicular appendages
  • Vas deferens

ASJC Scopus subject areas

  • Medicine(all)


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