Teratoma with trisomy 16 in a baboon (Papio hamadryas)

Charleen M. Moore, Jennifer Mckeand, Shelly M. Witte, Gene B. Hubbard, Jeffrey Rogers, M. Michelle Leland

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


A teratoma was found during a planned cesarean section in a 10-year-old primigravida baboon. This teratoma had a female sex chromosome complement and trisomy for chromosome 16. This is the first report of a teratoma in a baboon and the first report of a chromosomal abnormality in a nonhuman primate teratoma. It is also the first case in a nonhuman primate to address the mechanism of origin. Through the use of genetic markers from human chromosomes 5, 8 and 17, the origin of the teratoma was shown to be most consistent with failure of meiosis II or endoreduplication in a mature ovum, while the trisomy for chromosome 16 originated after the formation of the tumor.

Original languageEnglish (US)
Pages (from-to)323-332
Number of pages10
JournalAmerican Journal of Primatology
Issue number4
StatePublished - Dec 17 1998


  • Baboon
  • Teratoma
  • Trisomy

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Animal Science and Zoology


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