Temporal and regional trends of fractures in the United States: A review of the global burden of disease database

Background: Musculoskeletal diseases, including bone fractures, are a significant contributor to global disability. Understanding temporal and regional trends in bone fractures is crucial for effective healthcare planning and resource allocation. We sought to analyze recent epidemiological trends of different types of fractures in the United States and determine correlations and associations between fracture trends and potential influencing demographic factors (i.e. age, sex, regional-specific). Methods: Data from the Global Burden of Disease Database were analyzed to examine fracture incidence, prevalence, and years lived with disability (YLDs). Statistical analyses were conducted to determine temporal trends and sex-based differences. Results: The analysis revealed significant increases in hip fractures and decreases in pelvic fractures over time. Fractures of the patella, tibia, fibula, and ankle remain prevalent across all regions and sexes, with notable variations. Conclusions: These findings underscore the importance of targeted interventions and resource allocation to address the burden of fractures on public health. Despite limitations, this study provides critical insights into fracture epidemiology, guiding future prevention and management strategies.