Telomerase and the aging process

Research output: Contribution to journalShort survey

49 Scopus citations

Abstract

The level of telomerase activity is important in determining telomere length in aging cells and tissues. Here evidence on the importance of telomerase activity is reviewed with respect to aging rates of mammalian species and the health and life span of individuals within a species. The significance of telomerase reactivation for both cancer development and for immortalizing cells for therapeutic processes is assessed.

Original languageEnglish (US)
Pages (from-to)575-581
Number of pages7
JournalExperimental Gerontology
Volume42
Issue number7
DOIs
StatePublished - Jul 1 2007

Keywords

  • Cancer
  • Immortalization
  • Senescence
  • Telomerase
  • Telomeres

ASJC Scopus subject areas

  • Biochemistry
  • Aging
  • Molecular Biology
  • Genetics
  • Endocrinology
  • Cell Biology

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