Technical Considerations for Lung Transplantation in Kartagener's Syndrome

Jason M. Gauthier; Tsuyoshi Takahashi; Andrew J. Bierhals; Steven L. Brody; Ramsey R. Hachem; Chad A. Witt; Derek E. Byers; Roger D. Yusen; Elbert P. Trulock; Patrick R. Aguilar; Ruben G. Nava; Benjamin D. Kozower; Bryan F. Meyers; G. Alexander Patterson; Daniel Kreisel; Varun Puri

doi:10.1016/j.athoracsur.2018.08.095

Technical Considerations for Lung Transplantation in Kartagener's Syndrome

Jason M. Gauthier, Tsuyoshi Takahashi, Andrew J. Bierhals, Steven L. Brody, Ramsey R. Hachem, Chad A. Witt, Derek E. Byers, Roger D. Yusen, Elbert P. Trulock, Patrick R. Aguilar, Ruben G. Nava, Benjamin D. Kozower, Bryan F. Meyers, G. Alexander Patterson, Daniel Kreisel, Varun Puri

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Kartagener's syndrome is a rare genetic disorder of ciliated epithelial cells associated with recurrent respiratory tract infections, bronchiectasis, and situs inversus. In some patients, the accumulation of airway secretions and recurrent infections lead to end-stage lung disease, for which lung transplantation is the only effective treatment. Anatomical variations, such as dextrocardia and pulmonary situs inversus, make the procedure challenging, yet feasible with certain technical modifications and careful preparation of donor lungs. We report a case of bilateral lung transplantation without the use of cardiopulmonary bypass in a patient with Kartagener's syndrome while describing important technical details of the operation.

Original language	English (US)
Pages (from-to)	e337-e339
Journal	Annals of Thoracic Surgery
Volume	107
Issue number	5
DOIs	https://doi.org/10.1016/j.athoracsur.2018.08.095
State	Published - May 2019
Externally published	Yes

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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Gauthier, J. M., Takahashi, T., Bierhals, A. J., Brody, S. L., Hachem, R. R., Witt, C. A., Byers, D. E., Yusen, R. D., Trulock, E. P., Aguilar, P. R., Nava, R. G., Kozower, B. D., Meyers, B. F., Patterson, G. A., Kreisel, D., & Puri, V. (2019). Technical Considerations for Lung Transplantation in Kartagener's Syndrome. Annals of Thoracic Surgery, 107(5), e337-e339. https://doi.org/10.1016/j.athoracsur.2018.08.095

Gauthier, JM, Takahashi, T, Bierhals, AJ, Brody, SL, Hachem, RR, Witt, CA, Byers, DE, Yusen, RD, Trulock, EP, Aguilar, PR, Nava, RG, Kozower, BD, Meyers, BF, Patterson, GA, Kreisel, D & Puri, V 2019, 'Technical Considerations for Lung Transplantation in Kartagener's Syndrome', Annals of Thoracic Surgery, vol. 107, no. 5, pp. e337-e339. https://doi.org/10.1016/j.athoracsur.2018.08.095

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title = "Technical Considerations for Lung Transplantation in Kartagener's Syndrome",

abstract = "Kartagener's syndrome is a rare genetic disorder of ciliated epithelial cells associated with recurrent respiratory tract infections, bronchiectasis, and situs inversus. In some patients, the accumulation of airway secretions and recurrent infections lead to end-stage lung disease, for which lung transplantation is the only effective treatment. Anatomical variations, such as dextrocardia and pulmonary situs inversus, make the procedure challenging, yet feasible with certain technical modifications and careful preparation of donor lungs. We report a case of bilateral lung transplantation without the use of cardiopulmonary bypass in a patient with Kartagener's syndrome while describing important technical details of the operation.",

author = "Gauthier, {Jason M.} and Tsuyoshi Takahashi and Bierhals, {Andrew J.} and Brody, {Steven L.} and Hachem, {Ramsey R.} and Witt, {Chad A.} and Byers, {Derek E.} and Yusen, {Roger D.} and Trulock, {Elbert P.} and Aguilar, {Patrick R.} and Nava, {Ruben G.} and Kozower, {Benjamin D.} and Meyers, {Bryan F.} and Patterson, {G. Alexander} and Daniel Kreisel and Varun Puri",

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AU - Hachem, Ramsey R.

AU - Witt, Chad A.

AU - Byers, Derek E.

AU - Yusen, Roger D.

AU - Trulock, Elbert P.

AU - Aguilar, Patrick R.

AU - Nava, Ruben G.

AU - Kozower, Benjamin D.

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AU - Kreisel, Daniel

AU - Puri, Varun

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AB - Kartagener's syndrome is a rare genetic disorder of ciliated epithelial cells associated with recurrent respiratory tract infections, bronchiectasis, and situs inversus. In some patients, the accumulation of airway secretions and recurrent infections lead to end-stage lung disease, for which lung transplantation is the only effective treatment. Anatomical variations, such as dextrocardia and pulmonary situs inversus, make the procedure challenging, yet feasible with certain technical modifications and careful preparation of donor lungs. We report a case of bilateral lung transplantation without the use of cardiopulmonary bypass in a patient with Kartagener's syndrome while describing important technical details of the operation.

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Technical Considerations for Lung Transplantation in Kartagener's Syndrome

Abstract

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