Technical and clinical outcomes in concurrent multivessel occlusions treated with mechanical thrombectomy: Insights from the STAR collaboration

Hassan Saad, Sheila Eshraghi, Ali M. Alawieh, Feras Akbik, C. Michael Cawley, Brian M. Howard, Makenna Ash, Alice Hsu, Aqueel Pabaney, Ilko Maier, Sami Al Kasab, Kareem El Naamani, Pascal Jabbour, Joon Tae Kim, Stacey Q. Wolfe, Ansaar Rai, Robert M. Starke, Marios Nikos Psychogios, Amir Shaban, Adam S. ArthurShinichi Yoshimura, Isabel Fragata, Hugo H. Cuellar-Saenz, Adam J. Polifka, Justin Mascitelli, Joshua W. Osbun, Charles Matouk, Min S. Park, Michael R. Levitt, Travis M. Dumont, Richard Williamson, Alejandro M. Spiotta, Jonathan A. Grossberg

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background Endovascular thrombectomy (EVT) has become the mainstay treatment for large vessel occlusion, with favorable safety and efficacy profile. However, the safety and efficacy of EVT in concurrent multi-territory occlusions (MTVOs) remains unclear. Objective To investigate the prevalence, clinical and technical outcomes of concurrent EVT for MTVOs. Methods Data were included from the Stroke Thrombectomy and Aneurysm Registry (STAR) with 32 stroke centers for EVT performed to treat bilateral anterior or concurrent anterior and posterior circulation occlusions between 2017 and 2021. Patients with MTVO were identified, and propensity score matching was used to compare this group with patients with occlusion in a single arterial territory. Results Of a total of 7723 patients who underwent EVT for acute ischemic stroke, 54 (0.7%) underwent EVT for MTVOs (mean age 69±12.5; female 50%). 28% had bilateral and 72% had anterior and posterior circulations occlusions. The rate of successful recanalization (Thrombolysis in Cerebral Infarction 2b/3), complications, modified Rankin score at 90 days, and mortality was not significantly different between the matched cohorts. Multivariate analysis confirmed that MTVOs were not associated with poor functional outcome, symptomatic intracranial hemorrhage, or longer procedure time. Conclusion Compared with EVT for single vessel occlusions, EVT in appropriately selected patients with MTVOs has a similar efficacy and safety profile.

Original languageEnglish (US)
Pages (from-to)1072-1077
Number of pages6
JournalJournal of neurointerventional surgery
Issue number11
StatePublished - Nov 1 2023


  • intervention
  • stroke
  • thrombectomy

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery


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