Abstract
60 patients studied at the Tata Memorial Hospital from January 1976 to December 1982 were diagnosed as having T-cell acute lymphoblastic leukemia (ALL) by nonimmune rosette formation with sheep red blood cells. The analysis revealed a high incidence of mediastinal mass (50%) and extramedullary infiltration at presentation. The majority of patients (62%) presented with a high WBC count (>50,000/mm3). Unipolar acid phosphatase activity was observed in 90% of patients. The remission rate with a combination treatment of adriamycin, vincristine and prednisolone was found to be 95%. Long-term survival was around 30%. More aggressive or innovative treatments will be needed to improve the results in T-cell ALL.
Original language | English (US) |
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Pages (from-to) | 282-287 |
Number of pages | 6 |
Journal | Oncology |
Volume | 42 |
Issue number | 5 |
DOIs | |
State | Published - 1985 |
Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Cancer Research