Systemic lupus erythematosus: A consideration for antimicrobial prophylaxis

Monte K. Zysset, Michael T. Montgomery, Spencer W. Redding, Louis J. Dell'Italia

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Endothelial damage to heart valves, similar to that seen with rheumatic heart disease, occurs in 50% of all patients with systemic lupus erythematosus. Bacterial endocarditis is a consequence in 1% to 4% of these patients. This rate is greater than the incidence of endocarditis after rheumatic heart disease and compares favorably with the incidence of endocarditis in patients with prosthetic heart valves. At present, it is not possible to accurately delineate the subpopulation of patients with SLE that is at risk for this disease; hence, it is recommended that antibiotic prophylaxis (standard regimen suggested by the American Heart Association) be considered for all patients with systemic lupus erythematosus undergoing dental procedures associated with transient bacteremias.

Original languageEnglish (US)
Pages (from-to)30-34
Number of pages5
JournalOral Surgery, Oral Medicine, Oral Pathology
Issue number1
StatePublished - Jul 1987

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dentistry(all)


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