Abstract
A novel three-component cascade reaction was discovered and developed to synthesize pyridodiindoles with the assistance of microwave irradiation. A collection of pyridodiindoles was prepared by means of the mild reaction and simple operation procedure, which could be applicable to a broad scope of functional aldehydes. Screening demonstrated that compound 5g exhibited a good potency in HCT116 cell lines, and this work validated the feasibility of this novel reaction for generating promising bioactive compounds.
Original language | English (US) |
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Pages (from-to) | 7811-7815 |
Number of pages | 5 |
Journal | Organic Letters |
Volume | 20 |
Issue number | 24 |
DOIs | |
State | Published - Dec 21 2018 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry