Synthesis of a bone-targeted bortezomib with in vivo anti-myeloma effects in mice

Medicine and Dentistry

• Bisphosphonate 50%
• Bone 30%
• Bone Marrow 10%
• Bone Slice 10%
• Bortezomib 100%
• Chemotherapeutic Agent 10%
• Combination Therapy 20%
• Drug 10%
• Drug Dose Reduction 10%
• Growth 10%
• In Vitro 10%
• Malignant Neoplasm 10%
• Multiple Myeloma 50%
• Myeloma 10%
• Myeloma Cell 10%
• Neoplasm 10%
• Osteolysis 10%
• Patient 30%
• Proteasome Inhibitor 10%
• Side Effect 20%
• Therapeutic Procedure 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Bisphosphonic Acid Derivative 50%
• Bortezomib 100%
• Drug 10%
• Malignant Neoplasm 10%
• Mouse 10%
• Mouse Model 10%
• Multiple Myeloma 50%
• Myeloma 10%
• Neoplasm 10%
• Proteasome Inhibitor 10%
• Side Effect 20%