Synthesis and uptake of no-carrier-added 1-[11C]putrescine into rat prostate

P. A. Jerabek, C. S. Dence, M. R. Kilbourn, M. J. Welch, D. Kadmon

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

No carrier-added 1-[11C]putrescine has been prepared using a simple two-step procedure. Radiochemical yields of 1–2% at end-of-synthesis were obtained in a synthesis time of 50–60 min. The in vivo uptake of no carrier-added 1-[11C]putrescine into rat prostate was determined and compared to the uptake of no carrier-added material containing varying amounts of non-radioactive putrescine. The in vivo results indicate that the mechanism of uptake into the prostate is saturable.

Original languageEnglish (US)
Pages (from-to)349-352
Number of pages4
JournalInternational Journal of Nuclear Medicine and Biology
Volume12
Issue number5
DOIs
StatePublished - Jan 1 1985
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Synthesis and uptake of no-carrier-added 1-[<sup>11</sup>C]putrescine into rat prostate'. Together they form a unique fingerprint.

  • Cite this