No carrier-added 1-[11C]putrescine has been prepared using a simple two-step procedure. Radiochemical yields of 1–2% at end-of-synthesis were obtained in a synthesis time of 50–60 min. The in vivo uptake of no carrier-added 1-[11C]putrescine into rat prostate was determined and compared to the uptake of no carrier-added material containing varying amounts of non-radioactive putrescine. The in vivo results indicate that the mechanism of uptake into the prostate is saturable.
|Original language||English (US)|
|Number of pages||4|
|Journal||International Journal of Nuclear Medicine and Biology|
|State||Published - Jan 1 1985|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging