Synergy between Acute Intermittent Hypoxia and Task-Specific Training

Joseph F. Welch, Tommy W. Sutor, Alicia K. Vose, Raphael R. Perim, Emily J. Fox, Gordon S. Mitchell

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Acute intermittent hypoxia (AIH) and task-specific training (TST) synergistically improve motor function after spinal cord injury; however, mechanisms underlying this synergistic relation are unknown. We propose a hypothetical working model of neural network and cellular elements to explain AIH-TST synergy. Our goal is to forecast experiments necessary to advance our understanding and optimize the neurotherapeutic potential of AIH-TST.

Original languageEnglish (US)
Pages (from-to)125-132
Number of pages8
JournalExercise and Sport Sciences Reviews
Issue number3
StatePublished - Jul 1 2020
Externally publishedYes


  • acute intermittent hypoxia
  • exercise training
  • motor neuron
  • neuroplasticity
  • rehabilitation
  • spinal cord injury
  • spinal plasticity, phrenic

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation


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