Synaptic vesicle recycling

E. M. Lafer

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The mechanism of synaptic vesicle recycling has been hotly debated for more than 30 years. The various mechanistic models are presented, and the evidence supporting each model is discussed. It is now well accepted that endocytosis rates span an enormous range and are highly dependent on exocytosis rates. It is also well accepted that clathrin-mediated endocytosis plays a major role in synaptic vesicle recycling. However, it remains to be determined whether endocytic pathways with dramatically different rates operate using the same or different molecular mechanisms.

Original languageEnglish (US)
Title of host publicationHandbook of Neurochemistry and Molecular Neurobiology
Subtitle of host publicationNeural Membranes and Transport
PublisherSpringer US
Pages423-437
Number of pages15
ISBN (Print)9780387303468
DOIs
StatePublished - Dec 1 2007

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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