Endomyocardial biopsy is the accepted method of following immunosuppresed patients after orthotopic cardiac transplantations. Unfortunately the complication rate of biopsy is 3% and requires special expertise for interpretation of the tissue specimens. Other less invasive techniques have been sought using a catheter that analyzes right ventricular ejection fraction (RVEF) (RVEF Catheter Baxter Corporation). We retrospectively evaluated 61 procedures in 16 patients comparing the absolute RVEF and changes in RVEF with endomyocardial biopsy score. The mean biopsy score was 1.3 and RVEF was 30.5%. While no relation was severe for the group as a whole, individual patients did demonstrate an inverse correlation with the biopsy score size. Therefore measurements of RVEF might provide a less invasive and less costly means of following patients after transplantation.
|Original language||English (US)|
|Journal||Journal of Investigative Medicine|
|State||Published - Jan 1 1996|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)