TY - JOUR
T1 - Surgically induced necrotizing scleritis (SINS)
T2 - Is it a standalone condition or a variant of necrotizing scleritis?
AU - Magesan, Kowsigan
AU - Dutta Majumder, Parthopratim
AU - Agarwal, Mamta
AU - George, Amala E.
AU - Nair, Vinita
AU - Ganesh, Sudha K.
AU - Biswas, Jyotirmay
N1 - Publisher Copyright:
© 2024 Indian Journal of Ophthalmology.
PY - 2024/7
Y1 - 2024/7
N2 - Purpose: To report the clinical pattern of surgically induced necrotizing scleritis (SINS) in a tertiary eye care center in Southern India. Methods: Retrospective analysis of all SINS cases visiting the uveitis clinic of a tertiary eye institute between January 2009 and April 2019. Results: In total, 15 patients with a median age of 65 (IQR: 52-70) years were included in the study. Male (53%) predominance was noted, and SINS was unilateral (100%) in all cases. Most (87%) of the patients developed SINS after a single surgical procedure, with a median onset period of 251 (IQR: 127-1095) days. None of these patients had any evidence of systemic association. Ocular hypertension (n = 3, 20%), and cataract (n = 5, 33%) were the most common complications. When compared with a cohort of patients with idiopathic necrotizing scleritis, the index study did not find any statistically significant difference between SINS and idiopathic scleritis. Conclusion: SINS is idiopathic necrotizing scleritis rather than an independent entity of scleritis.
AB - Purpose: To report the clinical pattern of surgically induced necrotizing scleritis (SINS) in a tertiary eye care center in Southern India. Methods: Retrospective analysis of all SINS cases visiting the uveitis clinic of a tertiary eye institute between January 2009 and April 2019. Results: In total, 15 patients with a median age of 65 (IQR: 52-70) years were included in the study. Male (53%) predominance was noted, and SINS was unilateral (100%) in all cases. Most (87%) of the patients developed SINS after a single surgical procedure, with a median onset period of 251 (IQR: 127-1095) days. None of these patients had any evidence of systemic association. Ocular hypertension (n = 3, 20%), and cataract (n = 5, 33%) were the most common complications. When compared with a cohort of patients with idiopathic necrotizing scleritis, the index study did not find any statistically significant difference between SINS and idiopathic scleritis. Conclusion: SINS is idiopathic necrotizing scleritis rather than an independent entity of scleritis.
KW - Corticosteroid
KW - immunosuppression
KW - necrotizing scleritis
KW - surgically induced necrotizing scleritis
UR - https://www.scopus.com/pages/publications/85197628996
UR - https://www.scopus.com/pages/publications/85197628996#tab=citedBy
U2 - 10.4103/IJO.IJO_2724_23
DO - 10.4103/IJO.IJO_2724_23
M3 - Article
C2 - 38622865
AN - SCOPUS:85197628996
SN - 0301-4738
VL - 72
SP - S592-S595
JO - Indian Journal of Ophthalmology
JF - Indian Journal of Ophthalmology
IS - Suppl 4
ER -