Superficial temporal artery biopsy diagnostic for lung carcinoma

M. Tariq Bhatti, Jaime Furman, Shailesh Gupta, Homayoun Tabandeh, Ramin Monshizadeh

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


PURPOSE: To report a unique finding of metastatic tumor cells in the lumen of a superficial temporal artery biopsy specimen in a patient with severe visual loss and optic neuropathy. METHODS: Case report. RESULTS: A 69-year-old man presented with anorexia, pancranial headaches, and acute unilateral visual loss. Ophthalmic examination showed a visual acuity of no light perception and an amaurotic pupil in the left eye. Fundus examination was normal. A superficial temporal artery biopsy, performed for presumed arteritic posterior ischemic optic neuropathy, demonstrated intraluminal cells with irregular nuclei and prominent nucleoli suggestive of metastatic malignancy. Further systemic evaluation uncovered a poorly differentiated adenocarcinoma of the lung with intravascular infiltration and multiple distant metastases. CONCLUSION: Extensive systemic intravascular tumor embolization may be associated with optic neuropathy.

Original languageEnglish (US)
Pages (from-to)135-138
Number of pages4
JournalAmerican journal of ophthalmology
Issue number1
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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