99mTc-HMPAO-labeled WBC scan for the diagnosis of chronic recurrent multifocal osteomyelitis

Tyler A. Dailey; Michael D. Berven; Penny J. Vroman

doi:10.2967/jnmt.114.138073

^99mTc-HMPAO-labeled WBC scan for the diagnosis of chronic recurrent multifocal osteomyelitis

Tyler A. Dailey
, Michael D. Berven
, Penny J. Vroman

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The goal of this teaching case study is to demonstrate the novel use of ^99mTc-HMPAO-labeled white blood cells (WBCs) in diagnosing chronic recurrent multifocal osteomyelitis (CRMO). ^99mTc-HMPAO-labeled white blood cells were utilized to diagnose CRMO. Classically, CRMO is evaluated scintigraphically using ^99mTc-methylene diphosphonate/hydroxymethylene diphosphonate. ^99mTc-HMPAO-labeled WBCs were chosen over 111In-labeled WBCs because of the former's improved imaging characteristics and decreased radiation dose. ^99mTc- HMPAO-labeled WBCs were successful in diagnosing CRMO. ^99mTc-HMPAO-labeled WBC scanning is specific for the diagnosis of CRMO.

Original language	English (US)
Pages (from-to)	299-301
Number of pages	3
Journal	Journal of Nuclear Medicine Technology
Volume	42
Issue number	4
DOIs	https://doi.org/10.2967/jnmt.114.138073
State	Published - 2014
Externally published	Yes

Keywords

Bone scan
Chronic recurrent multifocal osteomyelitis
HMPAO
Pediatric

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

Access to Document

10.2967/jnmt.114.138073

Cite this

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title = "99mTc-HMPAO-labeled WBC scan for the diagnosis of chronic recurrent multifocal osteomyelitis",

abstract = "The goal of this teaching case study is to demonstrate the novel use of 99mTc-HMPAO-labeled white blood cells (WBCs) in diagnosing chronic recurrent multifocal osteomyelitis (CRMO). 99mTc-HMPAO-labeled white blood cells were utilized to diagnose CRMO. Classically, CRMO is evaluated scintigraphically using 99mTc-methylene diphosphonate/hydroxymethylene diphosphonate. 99mTc-HMPAO-labeled WBCs were chosen over 111In-labeled WBCs because of the former's improved imaging characteristics and decreased radiation dose. 99mTc- HMPAO-labeled WBCs were successful in diagnosing CRMO. 99mTc-HMPAO-labeled WBC scanning is specific for the diagnosis of CRMO.",

keywords = "Bone scan, Chronic recurrent multifocal osteomyelitis, HMPAO, Pediatric",

author = "Dailey, \{Tyler A.\} and Berven, \{Michael D.\} and Vroman, \{Penny J.\}",

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year = "2014",

doi = "10.2967/jnmt.114.138073",

language = "English (US)",

volume = "42",

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AU - Berven, Michael D.

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PY - 2014

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AB - The goal of this teaching case study is to demonstrate the novel use of 99mTc-HMPAO-labeled white blood cells (WBCs) in diagnosing chronic recurrent multifocal osteomyelitis (CRMO). 99mTc-HMPAO-labeled white blood cells were utilized to diagnose CRMO. Classically, CRMO is evaluated scintigraphically using 99mTc-methylene diphosphonate/hydroxymethylene diphosphonate. 99mTc-HMPAO-labeled WBCs were chosen over 111In-labeled WBCs because of the former's improved imaging characteristics and decreased radiation dose. 99mTc- HMPAO-labeled WBCs were successful in diagnosing CRMO. 99mTc-HMPAO-labeled WBC scanning is specific for the diagnosis of CRMO.

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KW - Chronic recurrent multifocal osteomyelitis

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