Sunrise-related headache: Case report

U. H. Ulas, A. Korkmaz, O. Karadas, Z. Odabasi, R. J. Reiter

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A male, 34 years of age, suffers from headaches, red and watery eyes. The headaches began in childhood; the frequency of headaches has increased over the years and in the last decade headaches have occurred on a daily basis. If he wakes up before sunrise he feels much better and free of a headache; however, once he continues to sleep during and after sunrise, he suffers from tiredness, headache and nervousness. On magnetic resonance imaging (MRI), benign neuroepithelial cysts or a chronic infarct area was reported at the junction of the left medio-lateral zone of hypothalamus. After repeated MRI examinations, it was decided that the lesion on the left medio-lateral zone of hypothalamus may have disrupted the pineal gland and changed melatonin secretion. It was decided to treat him with 3 mg melatonin daily before going to bed. After a week of treatment, the patient reported that he felt very fresh and was virtually free of headaches.

Original languageEnglish (US)
Pages (from-to)118-122
Number of pages5
Issue number1
StatePublished - Jan 1 2010
Externally publishedYes


  • Headache
  • Hypothalamic lesion
  • Melatonine

ASJC Scopus subject areas

  • Clinical Neurology


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