In dogs, the sequence of changes following IV and IM SCC consisted of an increase in IOP, fasciculations and then absence of twitch. During the experiments, no change in ICP occurred. With SCC given IV, the mean time until loss of twitch was 25 ± 7 sec. With SCC given IM the mean time was 52 ± 5 sec. Changes in IOP with time are shown in the figure. The increase in IOP with IV SCC was statistically significant only for a brief 10 sec. interval. On the other hand the statistically significant time of increased IOP with IM SCC was 14 min. 30 sec. Also, the magnitude of increase in IOP was greater with IM SCC administration than with IV administration. The highest points reaching 36.7 torr and 28.5 torr, respectively.
|Original language||English (US)|
|Issue number||3 SUPPL|
|State||Published - Jan 1 1979|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine