Subeschar antibiotic infusion in the treatment of burn wound infection.

W. F. McManus, A. D. Mason, Basil A Pruitt

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In a reproducible infected rat burn model, subeschar infusion of antibiotics failed to protect the animals from death via burn wound invasion excepting those animals receiving carbenicillin. Subcutaneous injection of maximal doses of carbenicillin at a distance from the burn wound protected these animals equally well. Some advantage was defined for the subeschar route of administration with suboptimal doses of carbenicillin. More important is the fact that propective selection of an effective antibiotic could not be made on the basis of in vitro antibiotic sensitivity tests.

Original languageEnglish (US)
Pages (from-to)1021-1023
Number of pages3
JournalJournal of Trauma
Volume20
Issue number12
StatePublished - Dec 1980
Externally publishedYes

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Carbenicillin
Wound Infection
Anti-Bacterial Agents
Wounds and Injuries
Subcutaneous Injections
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

McManus, W. F., Mason, A. D., & Pruitt, B. A. (1980). Subeschar antibiotic infusion in the treatment of burn wound infection. Journal of Trauma, 20(12), 1021-1023.

Subeschar antibiotic infusion in the treatment of burn wound infection. / McManus, W. F.; Mason, A. D.; Pruitt, Basil A.

In: Journal of Trauma, Vol. 20, No. 12, 12.1980, p. 1021-1023.

Research output: Contribution to journalArticle

McManus, WF, Mason, AD & Pruitt, BA 1980, 'Subeschar antibiotic infusion in the treatment of burn wound infection.', Journal of Trauma, vol. 20, no. 12, pp. 1021-1023.
McManus WF, Mason AD, Pruitt BA. Subeschar antibiotic infusion in the treatment of burn wound infection. Journal of Trauma. 1980 Dec;20(12):1021-1023.
McManus, W. F. ; Mason, A. D. ; Pruitt, Basil A. / Subeschar antibiotic infusion in the treatment of burn wound infection. In: Journal of Trauma. 1980 ; Vol. 20, No. 12. pp. 1021-1023.
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