Stillbirths in Macaca fascicularis

Wacharaporn Sesbuppha, Surachai Chantip, Edward J. Dick, Natalia E. Schlabritz-Loutsevitch, Rodolfo Guardado-Mendoza, Stephanie D. Butler, Patrice A. Frost, Gene B. Hubbard

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Backgrounds: Stillbirths in non-human primates are a major problem and represent failure of the maternal-fetal-placental unit to maintain normal relationships because of various endogenous, undetermined or environmental factors. Methods: Records of 236 stillborns and their dams in a Macaca fascicularis colony during a 7-year period were reviewed retrospectively. Results: The 7-year stillbirth incidence was 11.99% (236 stillbirths, 1967 live births). Most (61.02%, n = 144) were of undetermined etiology. Fetal causes included trauma (22.46%, n = 53), fetal pneumonia (0.85%, n = 2) and congenital anomalies (0.42%, n = 1). Maternal causes included dystocia (9.75%, n = 23) and uterine rupture (0.42%, n = 1). Forty-nine placentas were available for histologic evaluation; there was placentitis in five, necrosis in five and placental abruption in two. Most stillbirths occurred close to term. First stillbirths usually occurred in 8- to 12-year-old animals during the first six pregnancies. Conclusions: Most stillbirths were of undetermined etiology. Fetal trauma was the most common cause.

Original languageEnglish (US)
Pages (from-to)169-172
Number of pages4
JournalJournal of medical primatology
Issue number4
StatePublished - Aug 2008
Externally publishedYes


  • Cynomolgus
  • Dystocia
  • Fetus
  • Non-human primate
  • Placenta
  • Reproduction
  • Stillborn

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


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