Stem cells in alzheimer’s disease: Current standing and future challenges

Haitham Salem, Gabriela D. Colpo, Antonio L. Teixeira

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Abstract

To date, there is no definitive treatment for Alzheimer’s disease (AD). The realm of stem cells is very promising in regenerative medicine, particularly for neurodegenerative diseases. Various types of stem cells have been used in preclinical/clinical trials for AD aiming the development of an elusive disease modifying therapy. Over the last decade, much knowledge has been gained in this field regarding types of cells, routes and timing of administration, and outcomes of stem cells-based strategies for AD. In this chapter, we will trace the state of art and the challenges facing the use of stem cells in AD.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages93-102
Number of pages10
DOIs
StatePublished - 2018
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1079
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Alzheimer’s disease
  • Mesenchymal stem cells
  • Neuroinflammation
  • Neuronal stem cells

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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