Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees

Jeff T. Williams; Ravindranath Duggirala; John Blangero

doi:10.1002/(SICI)1098-2272(1997)14:6<1065::AID-GEPI84>3.0.CO;2-F

Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees

Jeff T. Williams, Ravindranath Duggirala, John Blangero

RAHC UME/GME Expansion

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

We investigated the statistical properties of a variance components method for quantitative trait linkage analysis using nuclear families and extended pedigrees.

Original language	English (US)
Pages (from-to)	1065-1070
Number of pages	6
Journal	Genetic epidemiology
Volume	14
Issue number	6
DOIs	https://doi.org/10.1002/(SICI)1098-2272(1997)14:6<1065::AID-GEPI84>3.0.CO;2-F
State	Published - 1997

Keywords

Power
Relative efficiency
Type I error rate
Unbiasedness

ASJC Scopus subject areas

Epidemiology
Genetics(clinical)

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10.1002/(SICI)1098-2272(1997)14:6<1065::AID-GEPI84>3.0.CO;2-F

Cite this

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title = "Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees",

abstract = "We investigated the statistical properties of a variance components method for quantitative trait linkage analysis using nuclear families and extended pedigrees.",

keywords = "Power, Relative efficiency, Type I error rate, Unbiasedness",

author = "Williams, {Jeff T.} and Ravindranath Duggirala and John Blangero",

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AU - Duggirala, Ravindranath

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N2 - We investigated the statistical properties of a variance components method for quantitative trait linkage analysis using nuclear families and extended pedigrees.

AB - We investigated the statistical properties of a variance components method for quantitative trait linkage analysis using nuclear families and extended pedigrees.

KW - Power

KW - Relative efficiency

KW - Type I error rate

KW - Unbiasedness

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Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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