Stability of Time-tradeoff Utilities in Survivors of Myocardial Infarction

Joel Tsevat, Lee Goldman, Jane R. Soukup, Gervasio A. Lamas, Kathleen F. Connors, Carole C. Chapin, Thomas H. Lee

Research output: Contribution to journalArticle

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Abstract

To investigate whether time-tradeoff utilities of survivors of myocardial infarction change over time and whether changes in utilities correlate with changes in functional status, the authors conducted serial interviews using a time tradeoff and three measures of functional status in a cohort of 67 patients who had recently had myocardial infarction. The patients were also asked to rate their overall health on a rating scale and were asked about chest pain, exercise status, and employment status. Each patient was interviewed two to five times over one and a half years. The mean (95% Cl) time-tradeoff score for all patients was 0.88 (0.84, 0.93). Over a mean interval of 8.4 months, 28 (42%) patients changed Karnofsky scores, 28 (42%) changed Specific Activity Scale classes, and 11 (16%) changed New York Heart Association classes, with most changes representing improvements in functional status. Scores on the rating scale improved by a mean (95% Cl) of 0.06 [(0.03, 0.10); p < 0.002], but scores on the time tradeoff remained stable, with a mean (95% Cl) change of 0.03 [(-0.02, 0.08); p = NS]. Changes in time-tradeoff scores did not correlate with changes in Specific Activity Scale classes (Kendall's τ = 0.21), New York Heart Association classes (τ = -0.02), or Karnofsky scores (τ = 0.14); with changes on the verbal rating scale (R = 0.20); with changes in chest pain status (τ = -0.05), exercise status (τ = 0.11), or employment status (τ = 0.11); or with interim hospitalizations (τ = 0.05). The authors conclude that, in this relatively stable group of survivors of myocardial infarction, time-tradeoff utilities remained stable, and that changes in time-tradeoff utilities did not correlate with changes in function. Key words: functional status; quality of life; utility; patient preferences; myocardial infarction.

Original languageEnglish (US)
Pages (from-to)161-165
Number of pages5
JournalMedical Decision Making
Volume13
Issue number2
DOIs
StatePublished - Jan 1 1993
Externally publishedYes

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Survivors
Myocardial Infarction
Chest Pain
Exercise
Patient Preference
Hospitalization
Quality of Life
Interviews
Health

ASJC Scopus subject areas

  • Health Policy

Cite this

Tsevat, J., Goldman, L., Soukup, J. R., Lamas, G. A., Connors, K. F., Chapin, C. C., & Lee, T. H. (1993). Stability of Time-tradeoff Utilities in Survivors of Myocardial Infarction. Medical Decision Making, 13(2), 161-165. https://doi.org/10.1177/0272989X9301300210

Stability of Time-tradeoff Utilities in Survivors of Myocardial Infarction. / Tsevat, Joel; Goldman, Lee; Soukup, Jane R.; Lamas, Gervasio A.; Connors, Kathleen F.; Chapin, Carole C.; Lee, Thomas H.

In: Medical Decision Making, Vol. 13, No. 2, 01.01.1993, p. 161-165.

Research output: Contribution to journalArticle

Tsevat, J, Goldman, L, Soukup, JR, Lamas, GA, Connors, KF, Chapin, CC & Lee, TH 1993, 'Stability of Time-tradeoff Utilities in Survivors of Myocardial Infarction', Medical Decision Making, vol. 13, no. 2, pp. 161-165. https://doi.org/10.1177/0272989X9301300210
Tsevat, Joel ; Goldman, Lee ; Soukup, Jane R. ; Lamas, Gervasio A. ; Connors, Kathleen F. ; Chapin, Carole C. ; Lee, Thomas H. / Stability of Time-tradeoff Utilities in Survivors of Myocardial Infarction. In: Medical Decision Making. 1993 ; Vol. 13, No. 2. pp. 161-165.
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